ATG4A 抗体 (Middle Region)
Our Local Distributor
北京 101111
Quick Overview for ATG4A 抗体 (Middle Region) (ABIN2775554)
抗原
See all ATG4A 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
原理
- ATG4A Antibody - middle region
-
序列
- PQSLGALGGK PNNAYYFIGF LGDELIFLDP HTTQTFVDTE ENGTVNDQTF
-
预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
-
产品特性
- This is a rabbit polyclonal antibody against ATG4A. It was validated on Western Blot.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human ATG4A
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
说明
-
We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42722-100UG
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- prevent freeze-thaw cycles
-
储存条件
- 4 °C,-20 °C
-
储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
-
-
: "Identification of breast cancer cell subtypes sensitive to ATG4B inhibition." in: Oncotarget, Vol. 7, Issue 41, pp. 66970-66988, (2016) (PubMed).
-
-
- ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))
-
别名
- ATG4A
-
背景
-
Background Information: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. ATG4A is a member of the autophagin protein family. ATG4A is also designated as a member of the C-54 family of cysteine proteases.
Gene Name: ATG4 autophagy related 4 homolog A (S. cerevisiae)
Alternative Symbols: APG4A, AUTL2
Protein Name: Cysteine protease ATG4A
-
分子量
- 45kDa
-
基因ID
- 115201
-
NCBI登录号
- NP_443168
-
UniProt
- Q8WYN0
-
途径
- Autophagy
抗原
-