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ATG4A 抗体 (Middle Region)

This anti-ATG4A antibody is a 兔 多克隆 antibody detecting ATG4A in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔 和 斑马鱼. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2775554
发货至: 中国

Quick Overview for ATG4A 抗体 (Middle Region) (ABIN2775554)

抗原

See all ATG4A 抗体
ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))

适用

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人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔, 斑马鱼

宿主

  • 50
  • 4
  • 2
  • 1

克隆类型

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多克隆

标记

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This ATG4A antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    PQSLGALGGK PNNAYYFIGF LGDELIFLDP HTTQTFVDTE ENGTVNDQTF

    预测反应

    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

    产品特性

    This is a rabbit polyclonal antibody against ATG4A. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human ATG4A
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 398 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Bortnik, Choutka, Horlings, Leung, Baker, Lebovitz, Dragowska, Go, Bally, Minchinton, Gelmon, Gorski: "Identification of breast cancer cell subtypes sensitive to ATG4B inhibition." in: Oncotarget, Vol. 7, Issue 41, pp. 66970-66988, (2016) (PubMed).

  • 抗原

    ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))

    别名

    ATG4A

    背景

    Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. ATG4A is a member of the autophagin protein family. ATG4A is also designated as a member of the C-54 family of cysteine proteases.
    Alias Symbols: APG4A, AUTL2
    Protein Interaction Partner: CDKL3, GABARAPL1, GABARAPL2, ATG101, MAP1LC3B,
    Protein Size: 398

    分子量

    45 kDa

    基因ID

    115201

    NCBI登录号

    NM_052936, NP_443168

    UniProt

    Q8WYN0

    途径

    Autophagy
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