ATG4A 抗体 (Middle Region)
Quick Overview for ATG4A 抗体 (Middle Region) (ABIN2775554)
抗原
See all ATG4A 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- Middle Region
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                                            序列
- PQSLGALGGK PNNAYYFIGF LGDELIFLDP HTTQTFVDTE ENGTVNDQTF
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                                            预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
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                                            产品特性
- This is a rabbit polyclonal antibody against ATG4A. It was validated on Western Blot.
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                                            纯化方法
- Affinity Purified
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                                            免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human ATG4A
 
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                                            应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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                                            说明
- 
                        Antigen size: 398 AA 
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                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            浓度
- Lot specific
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                                            缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            注意事项
- Avoid repeated freeze-thaw cycles.
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                                            储存条件
- -20 °C
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                                            储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
 
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    - 
                                            : "Identification of breast cancer cell subtypes sensitive to ATG4B inhibition."    in: Oncotarget, Vol. 7, Issue 41, pp. 66970-66988, (2016)         (PubMed).        
 
 
- 
                                            : "Identification of breast cancer cell subtypes sensitive to ATG4B inhibition."    in: Oncotarget, Vol. 7, Issue 41, pp. 66970-66988, (2016)         (PubMed).        
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    - ATG4A (Autophagy related 4A Cysteine Peptidase (ATG4A))
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                                            别名
- ATG4A
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                                            背景
- 
                        Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. ATG4A is a member of the autophagin protein family. ATG4A is also designated as a member of the C-54 family of cysteine proteases. 
 Alias Symbols: APG4A, AUTL2
 Protein Interaction Partner: CDKL3, GABARAPL1, GABARAPL2, ATG101, MAP1LC3B,
 Protein Size: 398
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                                            分子量
- 45 kDa
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                                            基因ID
- 115201
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                                            NCBI登录号
- NM_052936, NP_443168
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                                            UniProt
- Q8WYN0
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                                            途径
- Autophagy
 抗原
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