PPP4R2 抗体 (C-Term)
(1 reference)Our Local Distributor
北京 101111
Quick Overview for PPP4R2 抗体 (C-Term) (ABIN2775552)
抗原
See all PPP4R2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
序列
- DSRCTRQHCT EEDEEEDEEE EEESFMTSRE MIPERKNQEK ESDDALTVNE
-
预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
-
产品特性
- This is a rabbit polyclonal antibody against PPP4R2. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human PPP4R2
-
-
anti-Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) antibody
PPP4R2 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (Internal Region) antibodyPPP4R2 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (AA 1-360) antibodyPPP4R2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (Internal Region) antibodyPPP4R2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (Internal Region) antibodyPPP4R2 适用: 人, 猴 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (AA 288-337) antibodyPPP4R2 适用: 人, 小鼠, 猴, 大鼠, Cow, 马, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2) (C-Term) antibodyPPP4R2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 417 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
-
: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
-
: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
-
- PPP4R2 (Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2))
-
别名
- PPP4R2
-
背景
-
PPP4R2 is the regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). It may regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.
Alias Symbols: MGC131930, PP4R2
Protein Interaction Partner: UBC, PAAF1, SMEK1, SF3A1, CCDC6, VASP, CCT3, PSMA1, INPPL1, AMPD2, LRRC47, DSTN, PLIN3, NUBP2, TPM1, TRA2B, IGBP1, CLNS1A, PPP4C, SRRM2, TIPRL, SMEK2, GEMIN4, DDX20,
Protein Size: 417 -
分子量
- 47 kDa
-
基因ID
- 151987
-
NCBI登录号
- NM_174907, NP_777567
-
UniProt
- Q9NY27
抗原
-
