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PPP4R2 抗体 (C-Term)

This anti-PPP4R2 antibody is a 兔 多克隆 antibody detecting PPP4R2 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 马, Pig, 犬 和 兔. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2775552
发货至: 中国

Quick Overview for PPP4R2 抗体 (C-Term) (ABIN2775552)

抗原

See all PPP4R2 抗体
PPP4R2 (Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2))

适用

人, 小鼠, 大鼠, Cow, 马, Pig, 犬, 兔

宿主

  • 28

克隆类型

  • 28
多克隆

标记

  • 16
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PPP4R2 antibody is un-conjugated

应用范围

  • 20
  • 14
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 7
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    序列

    DSRCTRQHCT EEDEEEDEEE EEESFMTSRE MIPERKNQEK ESDDALTVNE

    预测反应

    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against PPP4R2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human PPP4R2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 417 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • 抗原

    PPP4R2 (Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2))

    别名

    PPP4R2

    背景

    PPP4R2 is the regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). It may regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.
    Alias Symbols: MGC131930, PP4R2
    Protein Interaction Partner: UBC, PAAF1, SMEK1, SF3A1, CCDC6, VASP, CCT3, PSMA1, INPPL1, AMPD2, LRRC47, DSTN, PLIN3, NUBP2, TPM1, TRA2B, IGBP1, CLNS1A, PPP4C, SRRM2, TIPRL, SMEK2, GEMIN4, DDX20,
    Protein Size: 417

    分子量

    47 kDa

    基因ID

    151987

    NCBI登录号

    NM_174907, NP_777567

    UniProt

    Q9NY27
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