DC-SIGN/CD209 抗体 (N-Term)
Quick Overview for DC-SIGN/CD209 抗体 (N-Term) (ABIN2775487)
抗原
See all DC-SIGN/CD209 (CD209) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- AGCLGHGPLV LQLLSFTLLA GLLVQVSKVP SSISQEQSRQ DAIYQNLTQL
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预测反应
- Human: 100%, Pig: 86%
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产品特性
- This is a rabbit polyclonal antibody against CD209. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CD209
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anti-CD209 (CD209) (AA 70-404) antibody
CD209 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD209 (CD209) antibodyCD209 适用: 人 WB, FACS, IHC, IF, ISt, StM 宿主: 小鼠 Monoclonal C209-1781 unconjugated
anti-CD209 (CD209) (AA 270-404) antibodyCD209 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 5C2A6 unconjugated
anti-CD209 (CD209) antibodyCD209 适用: 人 FACS, IHC, IP, IHC (p) 宿主: 大鼠 Monoclonal h209 unconjugated
anti-CD209 (CD209) (AA 1-404) antibodyCD209 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-CD209 (CD209) antibodyCD209 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-CD209 (CD209) (AA 115-238) antibodyCD209 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD209 (CD209) (AA 271-380) antibodyCD209 适用: 人 ELISA, IF, IP 宿主: 小鼠 Monoclonal 3B10 unconjugated
anti-CD209 (CD209) antibodyCD209 适用: 人 WB, FACS, IHC, IF, ISt, StM 宿主: 小鼠 Monoclonal rC209-1781 unconjugated Recombinant Antibody
anti-CD209 (CD209) antibodyCD209 适用: 人 FACS, IHC, ICC 宿主: 小鼠 Monoclonal UW60-1 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 404 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DC-SIGN/CD209 (CD209) (CD209)
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别名
- CD209
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背景
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This gene encodes a transmembrane receptor and is often referred to as DC-SIGN because of its expression on the surface of dendritic cells and macrophages. The encoded protein is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses with a large impact on public health. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. Variations in the number of 23 amino acid repeats in the neck domain of this protein are rare but have a significant impact on ligand binding ability. This gene is closely related in terms of both sequence and function to a neighboring gene (GeneID 10332, often referred to as L-SIGN). DC-SIGN and L-SIGN differ in their ligand-binding properties and distribution. Alternative splicing results in multiple variants.
Alias Symbols: CDSIGN, CLEC4L, DC-SIGN, DC-SIGN1, MGC129965
Protein Interaction Partner: VAC14, IKBKE, LSP1, CYLD, LGALS3BP, CEACAM5, CLU, CLEC4M, CD209, ICAM3, ICAM2, ITGAM, CEACAM1, SP1, HCVgp1,
Protein Size: 404 -
分子量
- 46 kDa
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基因ID
- 30835
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NCBI登录号
- NM_021155, NP_066978
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UniProt
- Q9NNX6
抗原
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