DKK4 抗体 (C-Term)
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- 抗原 See all DKK4 抗体
- DKK4 (Dickkopf Homolog 4 (Xenopus Laevis) (DKK4))
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抗原表位
- C-Term
- 适用
- 人, 小鼠, 豚鼠, 大鼠, 犬, 马, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DKK4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- RTSDCGPGLC CARHFWTKIC KPVLREGQVC SRRGHKDTAQ APEIFQRCDC
- 预测反应
- Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 79%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against Dkk4. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product DKK4 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 221 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- DKK4 (Dickkopf Homolog 4 (Xenopus Laevis) (DKK4))
- 别名
- Dkk4 (DKK4 产品)
- 背景
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Dkk4 antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Alias Symbols: Dkk-4, MGC25705
Protein Size: 221 - 分子量
- 24 kDa
- 基因ID
- 234130
- NCBI登录号
- NM_145592, NP_663567
- UniProt
- Q8VEJ3
- 途径
- WNT signaling
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