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DKK4 抗体 (C-Term)

The 兔 多克隆 anti-DKK4 antibody (ABIN2775398) specifically detects DKK4 in WB. The antibody is reactive with 人, 小鼠, 豚鼠, 大鼠, 犬, 马 和 兔 samples.
产品编号 ABIN2775398
发货至: 中国
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Quick Overview for DKK4 抗体 (C-Term) (ABIN2775398)

抗原

See all DKK4 抗体
DKK4 (Dickkopf Homolog 4 (Xenopus Laevis) (DKK4))

适用

人, 小鼠, 豚鼠, 大鼠, 犬, 马, 兔

宿主

  • 46
  • 3
  • 1

克隆类型

  • 48
  • 2
多克隆

标记

  • 25
  • 6
  • 4
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DKK4 antibody is un-conjugated

应用范围

  • 42
  • 25
  • 21
  • 4
  • 3
  • 3
  • 2
  • 2
Western Blotting (WB)
  • 抗原表位

    • 8
    • 8
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    序列

    RTSDCGPGLC CARHFWTKIC KPVLREGQVC SRRGHKDTAQ APEIFQRCDC

    预测反应

    Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 79%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against Dkk4. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 221 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    DKK4 (Dickkopf Homolog 4 (Xenopus Laevis) (DKK4))

    别名

    Dkk4

    背景

    Dkk4 antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
    Alias Symbols: Dkk-4, MGC25705
    Protein Size: 221

    分子量

    24 kDa

    基因ID

    234130

    NCBI登录号

    NM_145592, NP_663567

    UniProt

    Q8VEJ3

    途径

    WNT signaling
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