NNMT 抗体 (N-Term)
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北京 101111
Quick Overview for NNMT 抗体 (N-Term) (ABIN2775335)
抗原
See all NNMT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- NNMT Antibody - N-terminal region
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序列
- MESGFTSKDT YLSHFNPRDY LEKYYKFGSR HSAESQILKH LLKNLFKIFC
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预测反应
- Dog: 93%, Human: 100%, Mouse: 100%, Pig: 86%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against NNMT. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human NNMT
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42281-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink." in: Nature chemical biology, Vol. 9, Issue 5, pp. 300-6, (2013) (PubMed).
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- NNMT (Nicotinamide N-Methyltransferase (NNMT))
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别名
- NNMT
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背景
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Background Information: N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. NNMT responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor.N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. This gene encodes the protein responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor.
Gene Name: Nicotinamide N-methyltransferase
Protein Name: Nicotinamide N-methyltransferase
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分子量
- 29kDa
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基因ID
- 4837
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NCBI登录号
- NP_006160
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UniProt
- P40261
抗原
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