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NNMT 抗体 (N-Term)

There is 1 publication for this product available. The 兔 多克隆 anti-NNMT antibody is suitable to detect NNMT in samples from 人, 小鼠, 大鼠, 犬 和 Pig. It has been validated for WB.
产品编号 ABIN2775335
发货至: 中国
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Quick Overview for NNMT 抗体 (N-Term) (ABIN2775335)

抗原

See all NNMT 抗体
NNMT (Nicotinamide N-Methyltransferase (NNMT))

适用

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人, 小鼠, 大鼠, 犬, Pig

宿主

  • 43
  • 9
  • 2

克隆类型

  • 46
  • 8
多克隆

标记

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This NNMT antibody is un-conjugated

应用范围

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  • 1
Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    MESGFTSKDT YLSHFNPRDY LEKYYKFGSR HSAESQILKH LLKNLFKIFC

    预测反应

    Dog: 93%, Human: 100%, Mouse: 100%, Pig: 86%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against NNMT. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human NNMT
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Antigen size: 264 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ulanovskaya, Zuhl, Cravatt: "NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink." in: Nature chemical biology, Vol. 9, Issue 5, pp. 300-6, (2013) (PubMed).

  • 抗原

    NNMT (Nicotinamide N-Methyltransferase (NNMT))

    别名

    NNMT

    背景

    N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. NNMT responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor.N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. This gene encodes the protein responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor.
    Protein Interaction Partner: UBC, BMF, ATF6, APP,
    Protein Size: 264

    分子量

    29 kDa

    基因ID

    4837

    NCBI登录号

    NM_006169, NP_006160

    UniProt

    P40261
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