MAP3K14 抗体 (N-Term)
Quick Overview for MAP3K14 抗体 (N-Term) (ABIN2775274)
抗原
See all MAP3K14 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- SEAGPAAISI IAQAECENSQ EFSPTFSERI FIAGSKQYSQ SESLDQIPNN
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against MAP3K14. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MAP3K14
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 947 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))
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别名
- MAP3K14
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背景
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This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.
Alias Symbols: FTDCR1B, HS, HSNIK, NIK
Protein Interaction Partner: UBC, TRAF3, TRAF2, BIRC2, TRAF1, IKBKB, HSP90AA1, CHUK, TRAF6, TNAP, PELI3, TRAF5, TANK, NFKB2, ARRB2, ZFP91, EEF1A1, PEBP1, HSP90AB1, CDC37, MAP3K14, EDAR, IKBKAP, RPL6, RPL5, RIPK1, MAP3K7, MAPK3, CASP8, GRB14, GRB10, GRB7, MAP2K4, IKBKG, MAP3K8, RPL4,
Protein Size: 947 -
分子量
- 104 kDa
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基因ID
- 9020
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NCBI登录号
- NM_003954, NP_003945
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UniProt
- Q99558
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途径
- NF-kappaB Signaling, TCR Signaling
抗原
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