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DDX21 抗体 (C-Term)

This anti-DDX21 antibody is a 兔 多克隆 antibody detecting DDX21 in WB. Suitable for 人, 大鼠, 马, 犬, Pig, Cow, 豚鼠 和 兔. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN2775198
发货至: 中国

Quick Overview for DDX21 抗体 (C-Term) (ABIN2775198)

抗原

See all DDX21 抗体
DDX21 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21))

适用

  • 33
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
人, 大鼠, 马, 犬, Pig, Cow, 豚鼠, 兔

宿主

  • 33

克隆类型

  • 32
  • 1
多克隆

标记

  • 21
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DDX21 antibody is un-conjugated

应用范围

  • 22
  • 10
  • 7
  • 6
  • 6
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 8
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    序列

    FRGQRDGNRR FRGQREGSRG PRGQRSGGGN KSNRSQNKGQ KRSFSKAFGQ

    预测反应

    Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Pig: 93%, Rabbit: 93%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against DDX21. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human DDX21
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 783 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Miyazawa, Yoshikawa, Magae, Ishikawa, Izumikawa, Terukina, Suzuki, Nakamura-Fujiyama, Miura, Hayano, Komatsu, Isobe, Takahashi: "Human cell growth regulator Ly-1 antibody reactive homologue accelerates processing of preribosomal RNA." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 19, Issue 4, pp. 273-86, (2014) (PubMed).

    Romanova, Grand, Zhang, Rayner, Katoku-Kikyo, Kellner, Kikyo: "Critical role of nucleostemin in pre-rRNA processing." in: The Journal of biological chemistry, Vol. 284, Issue 8, pp. 4968-77, (2009) (PubMed).

  • 抗原

    DDX21 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (DDX21))

    别名

    DDX21

    背景

    DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX21 encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription.
    Alias Symbols: GUA, GURDB, RH-II/GU, RH-II/GuA
    Protein Interaction Partner: HUWE1, PA2G4, KPNA3, CEP250, SUMO2, SUMO3, STAU1, IVNS1ABP, UBC, MDM2, LGR4, SUMO1, ERG, WWOX, EED, rev, SRPK2, SRPK3, FBXO6, TARDBP, LYN, AICDA, PAN2, vif, WHSC1, VCAM1, ITGA4, IL7R, FN1, CSNK2A1, YWHAE, SMURF1, H2AFX, APTX, ESR1, FTSJ3, PCDHA2, RRP7A, R
    Protein Size: 783

    分子量

    86 kDa

    基因ID

    9188

    NCBI登录号

    NM_004728, NP_004719

    UniProt

    Q9NR30

    途径

    SARS-CoV-2 Protein Interactome
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