RENT1/UPF1 抗体 (Middle Region)
Quick Overview for RENT1/UPF1 抗体 (Middle Region) (ABIN2775184)
抗原
See all RENT1/UPF1 (UPF1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- RGTPKGKTGR GGRQKNRFGL PGPSQTNLPN SQASQDVASQ PFSQGALTQG
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 93%, Rat: 93%, Zebrafish: 83%
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产品特性
- This is a rabbit polyclonal antibody against UPF1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human UPF1
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anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 270-370) antibody
UPF1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 270-370) antibodyUPF1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) antibodyUPF1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) antibodyUPF1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 578-614), (Middle Region) antibodyUPF1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 301-450) antibodyUPF1 适用: 人 ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 583-612) antibodyUPF1 适用: 人 WB 宿主: 兔 Polyclonal RB8354 unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 1019-1116) antibodyUPF1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G3 unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 956-1125) antibodyUPF1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-UPF1 Regulator of Nonsense Transcripts Homolog (UPF1) (AA 1019-1116) antibodyUPF1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G3 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1118 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))
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别名
- UPF1
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背景
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UPF1 is a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. UPF1 is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene.This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ43809, FLJ46894, HUPF1, KIAA0221, NORF1, RENT1, pNORF1, smg-2
Protein Interaction Partner: UBC, SUMO2, STAU1, CDC37, IVNS1ABP, MOV10, DNA2, POP1, LIN28A, UPF3B, STAU2, UPF2, EZH2, BMI1, SUZ12, RNF2, GNPTG, RHOXF2, ACSS2, NADSYN1, PLEKHB2, PLEKHA5, TARDBP, RPRD2, ABHD16A, NDUFB10, DXO, SMG1, RUVBL2, RBM8A, SMG7, EIF4A3, RUVBL1, GSPT2, SMG5, GSPT
Protein Size: 1118 -
分子量
- 123 kDa
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基因ID
- 5976
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NCBI登录号
- NM_002911, NP_002902
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UniProt
- Q92900
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途径
- SARS-CoV-2 Protein Interactome
抗原
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