AKAP5 抗体 (Middle Region)
-
- 抗原 See all AKAP5 抗体
- AKAP5 (A Kinase (PRKA) Anchor Protein 5 (AKAP5))
-
抗原表位
- Middle Region
- 适用
- 人, 大鼠, 小鼠, Cow, 犬, 马, Pig, Saccharomyces cerevisiae
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This AKAP5 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- KQFLISAENE QVGVFANDNG FEDRTSEQYE TLLIETASSL VKNAIQLSIE
- 预测反应
- Cow: 86%, Dog: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 86%, Rat: 79%, Yeast: 82%
- 产品特性
- This is a rabbit polyclonal antibody against AKAP5. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human AKAP5
- Top Product
- Discover our top product AKAP5 Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 427 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- AKAP5 (A Kinase (PRKA) Anchor Protein 5 (AKAP5))
- 别名
- AKAP5 (AKAP5 产品)
- 物质类
- Viral Protein
- 背景
-
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP5 is a member of the AKAP family. It binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT.The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AKAP75, AKAP79, H21
Protein Interaction Partner: PRKACB, PRKACA, UBC, PRKCA, CALM1, GABRB1, GABRB3, IQGAP1, DLG4, DLG1, KCNJ2, PRKAR2B, PRKAR2A, RET, PPP3CA, ADRB2, Gria1, Grin2b,
Protein Size: 427 - 分子量
- 47 kDa
- 基因ID
- 9495
- NCBI登录号
- NM_004857, NP_004848
- UniProt
- P24588
- 途径
- cAMP Metabolic Process
-