DUX4 抗体 (N-Term)
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北京 101111
Quick Overview for DUX4 抗体 (N-Term) (ABIN2775040)
抗原
See all DUX4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- DUX4 Antibody - N-terminal region
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序列
- TRGAEGTLGG RQGGREAGRN GGRDRATQGL GAGPREPGTD GGRKAGRKSG
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预测反应
- Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against DUX4. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of human DUX4
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP36096-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- DUX4 (Double Homeobox 4 (DUX4))
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别名
- DUX4
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背景
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Background Information: This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length, a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that encodes two homeoboxes, the repeat-array and ORF is conserved in other mammals. The encoded protein has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1 (PITX1, GeneID 5307). Contraction of the macrosatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). Alternative splicing results in multiple transcript variants.
Gene Name: double homeobox 4
Alternative Symbols: DUX4L
Protein Name: double homeobox protein 4
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分子量
- 93kDa
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基因ID
- 100288687
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NCBI登录号
- NP_001280727
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UniProt
- Q9UBX2
抗原
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