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DUX4 抗体 (C-Term)

DUX4 适用: 人 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal P2B1 unconjugated
产品编号 ABIN863109
发货至: 中国
  • 抗原 See all DUX4 抗体
    DUX4 (Double Homeobox 4 (DUX4))
    抗原表位
    • 25
    • 15
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    C-Term
    适用
    • 77
    • 8
    • 8
    • 1
    • 1
    宿主
    • 60
    • 17
    小鼠
    克隆类型
    • 60
    • 15
    单克隆
    标记
    • 18
    • 8
    • 8
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DUX4 antibody is un-conjugated
    应用范围
    • 65
    • 32
    • 18
    • 15
    • 13
    • 13
    • 10
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    Detects ~45 kDa. No cross-reactivity with DUX4c.
    交叉反应
    人, 小鼠
    纯化方法
    Protein G Purified
    免疫原
    C-terminal 76 amino acids of DUX4 with glutathione-s-transferase (gst) tag
    克隆位点
    P2B1
    亚型
    IgG1
  • 应用备注
    • WB (1:1000)
    • ICC/IF (1:1000)
    • optimal dilutions for assays should be determined by the user.
    说明

    1 μg/ml of ABIN863109 was sufficient for detection of DUX4 in 20 μg of HeLa cell lysate by ECL immunoblot analysis using goat anti-mouse IgG: HRP as teh secondary.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C
  • 抗原
    DUX4 (Double Homeobox 4 (DUX4))
    别名
    DUX4 (DUX4 产品)
    别名
    DUX4 antibody, DUX4L antibody, double homeobox, 4 antibody, double homeobox 4 antibody, DUX4 antibody
    背景
    DUX4, or double homeobox4, is a human protein that is a transcriptional activator of paired-like homeodomain transcription factor 1 (1). Clinically it is a facioscapulohumeral muscular dystrophy candidate gene that appears to have a toxic gain of function (2-4). In FSHD individuals, the expression of the full-length DUX4 transcript is not completely suppressed in skeletal muscle and possibly other differentiated tissues (5).
    基因ID
    22947
    NCBI登录号
    NP_149418
    UniProt
    F5GZ66
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