UBE2C 抗体 (Middle Region)
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- 抗原 See all UBE2C 抗体
- UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This UBE2C antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- QGNICLDILK EKWSALYDVR TILLSIQSLL GEPNIDSPLN THAAELWKNP
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against UBE2C. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human UBE2C
- Top Product
- Discover our top product UBE2C Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 179 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))
- 别名
- UBE2C (UBE2C 产品)
- 别名
- LOC458287 antibody, UBCH10 antibody, dJ447F3.2 antibody, 1110015A16Rik antibody, D2Ertd695e antibody, im:7137135 antibody, zgc:123190 antibody, ubiquitin conjugating enzyme E2 C antibody, ubiquitin-conjugating enzyme E2C antibody, ubiquitin conjugating enzyme E2 C L homeolog antibody, ubiquitin conjugating enzyme E2 C S homeolog antibody, UBE2C antibody, NAEGRDRAFT_82946 antibody, ube2c.L antibody, Ube2c antibody, ube2c.S antibody, ube2c antibody
- 背景
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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2C is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for the destruction of mitotic cyclins and for cell cycle progression. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for the destruction of mitotic cyclins and for cell cycle progression. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
Alias Symbols: UBCH10, dJ447F3.2
Protein Interaction Partner: ANAPC11, FZR1, KLHL2, UBE2C, PCGF3, UBC, MAPK7, UBA1, BAG3, TNNC1, CXCR1, Rag1, TTC9C, UNK, ZFYVE19, UBQLN4, UBXN1, UBQLN1, UBXN7, TTLL12, SEC24A, AHCYL1, SSSCA1, YAP1, UBE4B, USP34, ZRANB2, ATP6V1F, USP9X, UBE2V1, UBE2B, TYMS, TRIP6, PSMC6, PSMA5, PPM1G,
Protein Size: 179 - 分子量
- 20 kDa
- 基因ID
- 11065
- NCBI登录号
- NM_007019, NP_008950
- UniProt
- O00762
- 途径
- Ubiquitin Proteasome Pathway
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