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UBE2C 抗体 (N-Term)

This anti-UBE2C antibody is a 兔 多克隆 antibody detecting UBE2C in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 和 斑马鱼.
产品编号 ABIN2774933
发货至: 中国

Quick Overview for UBE2C 抗体 (N-Term) (ABIN2774933)

抗原

See all UBE2C 抗体
UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))

适用

  • 78
  • 14
  • 13
  • 3
  • 3
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  • 2
  • 2
  • 2
  • 1
人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼

宿主

  • 62
  • 15
  • 1

克隆类型

  • 59
  • 18
  • 1
多克隆

标记

  • 43
  • 5
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  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
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This UBE2C antibody is un-conjugated

应用范围

  • 63
  • 36
  • 20
  • 13
  • 13
  • 13
  • 8
  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
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  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 10
    • 8
    • 6
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    • 1
    • 1
    • 1
    • 1
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    • 1
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    N-Term

    序列

    ELMTLMMSGD KGISAFPESD NLFKWVGTIH GAAGTVYEDL RYKLSLEFPS

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against UBE2C. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2C
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 179 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))

    别名

    UBE2C

    背景

    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2C is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for the destruction of mitotic cyclins and for cell cycle progression. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for the destruction of mitotic cyclins and for cell cycle progression. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
    Alias Symbols: UBCH10, dJ447F3.2
    Protein Interaction Partner: ANAPC11, FZR1, KLHL2, UBE2C, PCGF3, UBC, MAPK7, UBA1, BAG3, TNNC1, CXCR1, Rag1, TTC9C, UNK, ZFYVE19, UBQLN4, UBXN1, UBQLN1, UBXN7, TTLL12, SEC24A, AHCYL1, SSSCA1, YAP1, UBE4B, USP34, ZRANB2, ATP6V1F, USP9X, UBE2V1, UBE2B, TYMS, TRIP6, PSMC6, PSMA5, PPM1G,
    Protein Size: 179

    分子量

    20 kDa

    基因ID

    11065

    NCBI登录号

    NM_007019, NP_008950

    UniProt

    O00762

    途径

    Ubiquitin Proteasome Pathway
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