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MCM7 抗体 (Middle Region)

MCM7 适用: 人, 大鼠, 兔, 豚鼠, Cow, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2774887
发货至: 中国
  • 抗原 See all MCM7 抗体
    MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
    抗原表位
    • 27
    • 15
    • 13
    • 9
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 116
    • 30
    • 22
    • 10
    • 9
    • 9
    • 8
    • 8
    • 4
    • 2
    • 1
    人, 大鼠, 兔, 豚鼠, Cow, 马
    宿主
    • 80
    • 35
    • 2
    克隆类型
    • 76
    • 41
    多克隆
    标记
    • 70
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MCM7 antibody is un-conjugated
    应用范围
    • 78
    • 34
    • 31
    • 24
    • 21
    • 19
    • 13
    • 13
    • 12
    • 11
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    HRIVKMNKSE DDESGAGELT REELRQIAEE DFYEKLAASI APEIYGHEDV
    预测反应
    Cow: 92%, Guinea Pig: 85%, Horse: 92%, Human: 100%, Rabbit: 92%, Rat: 92%
    产品特性
    This is a rabbit polyclonal antibody against MCM7. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human MCM7
    Top Product
    Discover our top product MCM7 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 719 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
    别名
    MCM7 (MCM7 产品)
    别名
    CDC47 antibody, MCM2 antibody, P1.1-MCM3 antibody, P1CDC47 antibody, P85MCM antibody, PNAS146 antibody, MCM7 antibody, AI747533 antibody, Mcmd7 antibody, mCDC47 antibody, chunp6911 antibody, nyz175 antibody, sr:nyz175 antibody, cdc47 antibody, cdc47-2 antibody, mcm7 antibody, xmcm7 antibody, CG4978 antibody, DmMCM7 antibody, DmeMCM7 antibody, Dmel\\CG4978 antibody, McM7 antibody, Mcp-PCR1 antibody, PCR1 antibody, anon-EST:Liang-1.66 antibody, clone 1.66 antibody, minichromosome maintenance complex component 7 antibody, mini-chromosome maintenance complex protein 7 antibody, minichromosome maintenance complex component 2 antibody, minichromosome maintenance complex component 7 L homeolog antibody, Minichromosome maintenance 7 antibody, minichromosome maintenance complex component 7 S homeolog antibody, MCM complex subunit Mcm7 antibody, MCM7 antibody, CDC47 antibody, Mcm7 antibody, MCM2 antibody, mcm7 antibody, mcm7.L antibody, mcm7.S antibody
    背景
    MCM7 encodes a protein that is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme.The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
    Alias Symbols: MCM2, CDC47, P85MCM, P1CDC47, PNAS146, P1.1-MCM3
    Protein Interaction Partner: AK8, MIPOL1, C8orf34, USHBP1, MCMBP, CCDC102B, TRIM54, MBIP, UBQLN1, TRIM27, NAB2, KIFC3, GOLGA2, PNMA1, UBC, SP2, HAUS2, CEP250, CEP57, SUMO2, SUMO3, PCNA, STAU1, SUZ12, RNF2, MCM4, MCM2, HSP90AB1, PRMT1, PRRC1, CLUH, TOMM34, TRIM16, HYOU1, BAG3, MIB1, P
    Protein Size: 719
    分子量
    81 kDa
    基因ID
    4176
    NCBI登录号
    NM_005916, NP_005907
    UniProt
    P33993
    途径
    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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