MCM7 抗体 (Middle Region)
Our Local Distributor
北京 101111
Quick Overview for MCM7 抗体 (Middle Region) (ABIN2774887)
抗原
See all MCM7 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
序列
- HRIVKMNKSE DDESGAGELT REELRQIAEE DFYEKLAASI APEIYGHEDV
-
预测反应
- Cow: 92%, Guinea Pig: 85%, Horse: 92%, Human: 100%, Rabbit: 92%, Rat: 92%
-
产品特性
- This is a rabbit polyclonal antibody against MCM7. It was validated on Western Blot and immunohistochemistry.
-
纯化方法
- Protein A purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human MCM7
-
-
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 1-389) antibody
MCM7 适用: 人 WB, IF, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 6C2 unconjugated
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 360-719) antibodyMCM7 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 7 (MCM7) antibodyMCM7 适用: 人 WB, IF, IHC (p), ICC, IP, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 526-719) antibodyMCM7 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (Internal Region) antibodyMCM7 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 195-319) antibodyMCM7 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal MCM7-1466 unconjugated
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 195-319) antibodyMCM7 适用: 人 WB, IHC, StM 宿主: 兔 Monoclonal MCM7-2832R unconjugated Recombinant Antibody
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 195-319) antibodyMCM7 适用: 人 IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal MCM7-1467 unconjugated
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 195-319) antibodyMCM7 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal rMCM7-1468 unconjugated Recombinant Antibody
anti-Minichromosome Maintenance Complex Component 7 (MCM7) antibodyMCM7 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 719 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
-
别名
- MCM7
-
背景
-
MCM7 encodes a protein that is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme.The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: MCM2, CDC47, P85MCM, P1CDC47, PNAS146, P1.1-MCM3
Protein Interaction Partner: AK8, MIPOL1, C8orf34, USHBP1, MCMBP, CCDC102B, TRIM54, MBIP, UBQLN1, TRIM27, NAB2, KIFC3, GOLGA2, PNMA1, UBC, SP2, HAUS2, CEP250, CEP57, SUMO2, SUMO3, PCNA, STAU1, SUZ12, RNF2, MCM4, MCM2, HSP90AB1, PRMT1, PRRC1, CLUH, TOMM34, TRIM16, HYOU1, BAG3, MIB1, P
Protein Size: 719 -
分子量
- 81 kDa
-
基因ID
- 4176
-
NCBI登录号
- NM_005916, NP_005907
-
UniProt
- P33993
-
途径
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
抗原
-
