MCM3 抗体 (C-Term)
Quick Overview for MCM3 抗体 (C-Term) (ABIN2774880)
抗原
See all MCM3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- SQEDQEQKRK RRKTRQPDAK DGDSYDPYDF SDTEEEMPQV HTPKTADSQE
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预测反应
- Cow: 92%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 93%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against MCM3. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human MCM3
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anti-Minichromosome Maintenance Complex Component 3 (MCM3) (AA 699-808) antibody
MCM3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4F7 unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) (AA 1-295) antibodyMCM3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) antibodyMCM3 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) (AA 699-808) antibodyMCM3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3E1 unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) (AA 13-27), (N-Term) antibodyMCM3 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) (AA 1-295) antibodyMCM3 适用: 人 WB, IHC, ELISA, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) antibodyMCM3 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) antibodyMCM3 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-503M unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) (AA 726-775) antibodyMCM3 适用: 人, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) (AA 696-745) antibodyMCM3 适用: 人, 猴, Cow, 豚鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 808 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))
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别名
- MCM3
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背景
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MCM3 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.
Alias Symbols: HCC5, MGC1157, P1-MCM3, P1.h, RLFB
Protein Interaction Partner: SUMO2, MCMBP, UBC, KEAP1, MDM2, MCM6, MCM5, ACTBL2, MGEA5, CAP1, SAE1, HSP90B1, TPM3, HSP90AA1, FKBP5, FKBP4, MIB1, YWHAQ, UBD, TCEA1, MCM10, ORC5, ORC4, MCM2, ITGA4, FN1, CSNK2A1, CDK2, CDC6, CDC5L, PNKP, CDC7, VCAM1, NOTCH1, POLD1, POLA1, MCM7, PIPSL, P
Protein Size: 808 -
分子量
- 89 kDa
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基因ID
- 4172
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NCBI登录号
- NM_002388, NP_002379
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UniProt
- P25205
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途径
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
抗原
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