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GJB2 抗体 (Middle Region)

This anti-GJB2 antibody is a 兔 多克隆 antibody detecting GJB2 in WB. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 和 绵羊.
产品编号 ABIN2774858
发货至: 中国

Quick Overview for GJB2 抗体 (Middle Region) (ABIN2774858)

抗原

See all GJB2 抗体
GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))

适用

人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 绵羊

宿主

  • 48
  • 5
  • 1

克隆类型

  • 49
  • 5
多克隆

标记

  • 35
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GJB2 antibody is un-conjugated

应用范围

  • 38
  • 29
  • 23
  • 7
  • 6
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB)
  • 抗原表位

    • 7
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    序列

    STPALLVAMH VAYRRHEKKR KFIKGEIKSE FKDIEEIKTQ KVRIEGSLWW

    预测反应

    Cow: 86%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 79%, Rat: 93%, Sheep: 86%

    产品特性

    This is a rabbit polyclonal antibody against GJB2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human GJB2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 226 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))

    别名

    GJB2

    背景

    Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels. Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ. The connexins are designated by their molecular mass. Another system of nomenclature divides gap junction proteins into 2 categories, alpha and beta, according to sequence similarities at the nucleotide and amino acid levels. For example, CX43 (MIM 121014) is designated alpha-1 gap junction protein, whereas CX32 (GJB1, MIM 304040) and CX26 are called beta-1 and beta-2 gap junction proteins, respectively. This nomenclature emphasizes that CX32 and CX26 are more homologous to each other than either of them is to CX43.
    Alias Symbols: HID, KID, PPK, CX26, DFNA3, DFNB1, NSRD1, DFNA3A, DFNB1A
    Protein Interaction Partner: CD14, CNST, FBXO2, SKP1, UBC, GJB6, CAV1, GJB1,
    Protein Size: 226

    分子量

    25 kDa

    基因ID

    2706

    NCBI登录号

    NM_004004, NP_003995

    UniProt

    P29033

    途径

    Sensory Perception of Sound, Cell-Cell Junction Organization
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