GJB2 抗体 (Middle Region)
Quick Overview for GJB2 抗体 (Middle Region) (ABIN2774858)
抗原
See all GJB2 抗体适用
宿主
克隆类型
标记
应用范围
- 
    - 
                                            抗原表位
- Middle Region
- 
                                            序列
- STPALLVAMH VAYRRHEKKR KFIKGEIKSE FKDIEEIKTQ KVRIEGSLWW
- 
                                            预测反应
- Cow: 86%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 79%, Rat: 93%, Sheep: 86%
- 
                                            产品特性
- This is a rabbit polyclonal antibody against GJB2. It was validated on Western Blot using a cell lysate as a positive control.
- 
                                            纯化方法
- Protein A purified
- 
                                            免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human GJB2
 
- 
                                            
- 
    
- 
    - 
                                            应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 
                                            说明
- 
                        Antigen size: 226 AA 
- 
                                            限制
- 仅限研究用
 
- 
                                            
- 
    - 
                                            状态
- Liquid
- 
                                            浓度
- Lot specific
- 
                                            缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 
                                            储存液
- Sodium azide
- 
                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            注意事项
- Avoid repeated freeze-thaw cycles.
- 
                                            储存条件
- -20 °C
- 
                                            储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
 
- 
                                            
- 
    - GJB2 (Gap Junction Protein, beta 2, 26kDa (GJB2))
- 
                                            别名
- GJB2
- 
                                            背景
- 
                        Gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels. Proteins, called connexins, purified from fractions of enriched gap junctions from different tissues differ. The connexins are designated by their molecular mass. Another system of nomenclature divides gap junction proteins into 2 categories, alpha and beta, according to sequence similarities at the nucleotide and amino acid levels. For example, CX43 (MIM 121014) is designated alpha-1 gap junction protein, whereas CX32 (GJB1, MIM 304040) and CX26 are called beta-1 and beta-2 gap junction proteins, respectively. This nomenclature emphasizes that CX32 and CX26 are more homologous to each other than either of them is to CX43.
 Alias Symbols: HID, KID, PPK, CX26, DFNA3, DFNB1, NSRD1, DFNA3A, DFNB1A
 Protein Interaction Partner: CD14, CNST, FBXO2, SKP1, UBC, GJB6, CAV1, GJB1,
 Protein Size: 226
- 
                                            分子量
- 25 kDa
- 
                                            基因ID
- 2706
- 
                                            NCBI登录号
- NM_004004, NP_003995
- 
                                            UniProt
- P29033
- 
                                            途径
- Sensory Perception of Sound, Cell-Cell Junction Organization
 抗原
- 
                    
 
                                     
                                     
                                    