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RNF128 抗体 (C-Term)

This 兔 多克隆 anti-RNF128 antibody specifically detects RNF128 in WB. The antibody is reactive with 人, 小鼠, 大鼠, 犬, 豚鼠, Cow, 马 和 兔 samples.
产品编号 ABIN2774780
发货至: 中国
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Quick Overview for RNF128 抗体 (C-Term) (ABIN2774780)

抗原

See all RNF128 抗体
RNF128 (Ring Finger Protein 128 (RNF128))

适用

  • 35
  • 20
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  • 2
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  • 2
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  • 2
人, 小鼠, 大鼠, 犬, 豚鼠, Cow, 马, 兔

宿主

  • 35

克隆类型

  • 35
多克隆

标记

  • 12
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
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  • 1
This RNF128 antibody is un-conjugated

应用范围

  • 30
  • 13
  • 12
  • 4
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 7
    • 6
    • 3
    • 2
    • 1
    C-Term

    序列

    LEEHVQSTNE SLQLVNHEAN SVAVDVIPHV DNPTFEEDET PNQETAVREI

    预测反应

    Cow: 86%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against RNF128. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human RNF128
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 428 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    RNF128 (Ring Finger Protein 128 (RNF128))

    别名

    RNF128

    背景

    RNF128 is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of RNF128 in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of RNF128 was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype.The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
    Alias Symbols: FLJ23516, GRAIL
    Protein Interaction Partner: CEP76, APPBP2, TP53, UBE2H, UBE2E1, UBE2D1, Arhgdia, Arhgdib, RNF128, UBE2T, UBE2I, UBE2N, CD40LG, OTUB1, USP8,
    Protein Size: 428

    分子量

    47 kDa

    基因ID

    79589

    NCBI登录号

    NM_194463, NP_919445

    UniProt

    Q8TEB7
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