RNF128 抗体 (C-Term)
Quick Overview for RNF128 抗体 (C-Term) (ABIN2774780)
抗原
See all RNF128 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- LEEHVQSTNE SLQLVNHEAN SVAVDVIPHV DNPTFEEDET PNQETAVREI
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预测反应
- Cow: 86%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against RNF128. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human RNF128
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 428 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RNF128 (Ring Finger Protein 128 (RNF128))
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别名
- RNF128
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背景
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RNF128 is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of RNF128 in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of RNF128 was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype.The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: FLJ23516, GRAIL
Protein Interaction Partner: CEP76, APPBP2, TP53, UBE2H, UBE2E1, UBE2D1, Arhgdia, Arhgdib, RNF128, UBE2T, UBE2I, UBE2N, CD40LG, OTUB1, USP8,
Protein Size: 428 -
分子量
- 47 kDa
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基因ID
- 79589
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NCBI登录号
- NM_194463, NP_919445
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UniProt
- Q8TEB7
抗原
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