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RNF128 抗体 (AA 229-400)

RNF128 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7151138
发货至: 中国
  • 抗原 See all RNF128 抗体
    RNF128 (Ring Finger Protein 128 (RNF128))
    抗原表位
    • 7
    • 5
    • 3
    • 2
    • 1
    AA 229-400
    适用
    • 34
    • 21
    • 19
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    宿主
    • 34
    克隆类型
    • 34
    多克隆
    标记
    • 11
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RNF128 antibody is un-conjugated
    应用范围
    • 29
    • 13
    • 11
    • 4
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    交叉反应
    人, 小鼠
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human E3 ubiquitin-protein ligase RNF128 protein (229-400AA)
    亚型
    IgG
    Top Product
    Discover our top product RNF128 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    RNF128 (Ring Finger Protein 128 (RNF128))
    别名
    RNF128 (RNF128 产品)
    别名
    rnf128 antibody, wu:fb57h05 antibody, zgc:77843 antibody, 1300002C13Rik antibody, AI987883 antibody, GRAIL antibody, Greul1 antibody, RGD1566282 antibody, grail antibody, greul1 antibody, ring finger protein 128a antibody, ring finger protein 128, E3 ubiquitin protein ligase antibody, ring finger protein 128 antibody, ring finger protein 128, E3 ubiquitin protein ligase L homeolog antibody, rnf128a antibody, RNF128 antibody, Rnf128 antibody, rnf128.L antibody
    背景

    Background: E3 ubiquitin-protein ligase that catalyzes \\\'Lys-48\\\'- and \\\'Lys-63\\\'-linked polyubiquitin chains formation. Functions as an inhibitor of cytokine gene transcription. Inhibits IL2 and IL4 transcription, thereby playing an important role in the induction of the anergic phenotype, a long-term stable state of T-lymphocyte unresponsiveness to antigenic stimulation associated with the blockade of interleukin production. Ubiquitinates ARPC5 with \\\'Lys-48\\\' linkages and COR1A with \\\'Lys-63\\\' linkages leading to their degradation, down-regulation of these cytosleletal components results in impaired lamellipodium formation and reduced accumulation of F-actin at the immunological synapse. Functions in the patterning of the dorsal ectoderm, sensitizes ectoderm to respond to neural-inducing signals.

    Aliases: E3 ubiquitin protein ligase RNF128 antibody, E3 ubiquitin-protein ligase RNF128 antibody, FLJ23516 antibody, Gene related to anergy in lymphocytes protein antibody, GRAIL antibody, RING finger protein 128 antibody, RN128_HUMAN antibody, RNF128 antibody

    UniProt
    Q8TEB7
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