DTX2 抗体 (C-Term)
Quick Overview for DTX2 抗体 (C-Term) (ABIN2774772)
抗原
See all DTX2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- EDCGTILIVY SIPHGIQGPE HPNPGKPFTA RGFPRQCYLP DNAQGRKVLE
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预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against DTX2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human DTX2
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anti-Deltex Homolog 2 (DTX2) (AA 1-622) antibody
DTX2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Deltex Homolog 2 (DTX2) (AA 1-280) antibodyDTX2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Deltex Homolog 2 (DTX2) (AA 1-280) antibodyDTX2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Deltex Homolog 2 (DTX2) (Internal Region) antibodyVerified DTX2 适用: 人 IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Deltex Homolog 2 (DTX2) (AA 454-503) antibodyDTX2 适用: 人, 小鼠, 大鼠, 犬, Cow, 山羊, 豚鼠, 马, 兔, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Deltex Homolog 2 (DTX2) (AA 1-622) antibodyDTX2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Deltex Homolog 2 (DTX2) antibodyDTX2 适用: 人, 犬, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 575 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DTX2 (Deltex Homolog 2 (DTX2))
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别名
- DTX2
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背景
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DTX2 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. DTX2 probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context and mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. It also functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Alias Symbols: KIAA1528, MGC71098, RNF58
Protein Interaction Partner: KRTAP26-1, RFX6, KLC3, GLYCTK, DTX2, RIMBP3, C1orf94, NCALD, PLEKHF2, TRIM54, EIF4ENIF1, ALKBH4, UBE2D4, HPCAL4, SPG21, SEC22A, SPAG8, STX12, NCS1, FAM168A, RBPMS, SEC23B, ABHD16A, VSNL1, SUMO1, UBE2D3, UBE2D1, UBC, TRIP6, QARS, HDC, GOLGA2, FHL2, ARNT2,
Protein Size: 575 -
分子量
- 62 kDa
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基因ID
- 113878
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NCBI登录号
- NM_001102596, NP_001096066
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UniProt
- Q6XM87
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途径
- Notch Signaling
抗原
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