MKRN1 抗体 (N-Term)
Quick Overview for MKRN1 抗体 (N-Term) (ABIN2774707)
抗原
See all MKRN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- GDRCRYEHSK PLKQEEATAT ELTTKSSLAA SSSLSSIVGP LVEMNTGEAE
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 83%, Rat: 100%, Zebrafish: 77%
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产品特性
- This is a rabbit polyclonal antibody against MKRN1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MKRN1
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anti-Makorin Ring Finger Protein 1 (MKRN1) antibody
MKRN1 适用: 人 WB, IHC, IHC (p), FACS 宿主: 小鼠 Monoclonal 2C8 unconjugated
anti-Makorin Ring Finger Protein 1 (MKRN1) (AA 105-118) antibodyVerified MKRN1 适用: 人, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Makorin Ring Finger Protein 1 (MKRN1) (AA 365-440) antibodyMKRN1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E9 unconjugated
anti-Makorin Ring Finger Protein 1 (MKRN1) antibodyMKRN1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Makorin Ring Finger Protein 1 (MKRN1) (AA 109-209) antibodyMKRN1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Makorin Ring Finger Protein 1 (MKRN1) (AA 371-420) antibodyMKRN1 适用: 人, 小鼠, 犬, 豚鼠, 马, 兔, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Makorin Ring Finger Protein 1 (MKRN1) (AA 101-150) antibodyMKRN1 适用: 人, 小鼠, 犬, Cow, 豚鼠, 马, 大鼠, Pig, 斑马鱼, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Makorin Ring Finger Protein 1 (MKRN1) (N-Term) antibodyMKRN1 适用: 人, 小鼠, 犬, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Makorin Ring Finger Protein 1 (MKRN1) (C-Term) antibodyMKRN1 适用: 人, 小鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 147 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MKRN1 (Makorin Ring Finger Protein 1 (MKRN1))
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别名
- MKRN1
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背景
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The Makorin ring finger protein-1 gene (MKRN1) is a highly transcribed, intron-containing source for a family of intronless mammalian genes encoding a novel class of zinc finger proteins. Phylogenetic analyses indicate that the MKRN1 gene is the ancestral founder of this gene family.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.
Alias Symbols: FLJ21334, RNF61
Protein Interaction Partner: UBC, TP53, CDKN1A, FADD, MAP1LC3B, UBE2W, DUSP23, CSNK1G1, UBE2D3, TERT, EXOSC8,
Protein Size: 147 -
分子量
- 16 kDa
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基因ID
- 23608
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NCBI登录号
- NM_003338, NP_038474
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UniProt
- Q9UHC7
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途径
- Chromatin Binding
抗原
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