FBXW11 抗体 (N-Term)
(1 reference)Quick Overview for FBXW11 抗体 (N-Term) (ABIN2774702)
抗原
See all FBXW11 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- CLQSMPSVRC LQISNGTSSV IVSRKRPSEG NYQKEKDLCI KYFDQWSESD
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against FBXW11. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human FBXW11
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anti-F-Box and WD Repeat Domain Containing 11 (FBXW11) (AA 1-140) antibody
FBXW11 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 11 (FBXW11) (AA 1-529) antibodyFBXW11 适用: 人 ELISA, IF, PLA 宿主: 小鼠 Monoclonal 2E7 unconjugated
anti-F-Box and WD Repeat Domain Containing 11 (FBXW11) (AA 1-140) antibodyFBXW11 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 11 (FBXW11) (AA 168-196) antibodyFBXW11 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18056 unconjugated
anti-F-Box and WD Repeat Domain Containing 11 (FBXW11) (AA 175-204), (Middle Region) antibodyFBXW11 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 11 (FBXW11) (N-Term) antibodyFBXW11 适用: 人, 小鼠, 犬, 豚鼠, 兔, 小鸡, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 11 (FBXW11) (AA 38-87) antibodyFBXW11 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 马, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 542 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
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: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
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- FBXW11 (F-Box and WD Repeat Domain Containing 11 (FBXW11))
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别名
- FBXW11
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背景
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FBXW11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.
Alias Symbols: BTRC2, BTRCP2, FBW1B, FBXW1B, Fbw11, Hos, KIAA0696
Protein Interaction Partner: ELMO2, NCKAP5L, USP37, CACHD1, ZNF395, TACC1, STK4, STK3, SKP1, REST, RELA, RAP1GAP, PFDN5, PFDN4, NRD1, NFKB2, NFKB1, NFE2L2, NEDD8, MAX, LRCH4, ILF3, FOXN2, HNRNPU, HIVEP2, HIVEP1, HCFC1, EZH2, DOCK1, DHX9, CTNNB1, CTNNA1, CLTC, CHD1, CDC34, CDC25B, CDC
Protein Size: 542 -
分子量
- 62 kDa
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基因ID
- 23291
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NCBI登录号
- NM_012300, NP_036432
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UniProt
- Q9UKB1
抗原
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