RNF139 抗体 (N-Term)
Quick Overview for RNF139 抗体 (N-Term) (ABIN2774685)
抗原
See all RNF139 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- SQRSLFKFYT YSSAFLLAAT SVLVNYYASL HIDFYGAYNT SAFGIELLPR
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 87%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against RNF139. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human RNF139
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anti-Ring Finger Protein 139 (RNF139) (AA 565-664) antibody
RNF139 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D10 unconjugated
anti-Ring Finger Protein 139 (RNF139) (AA 72-121) antibodyRNF139 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, Bat, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 139 (RNF139) (AA 510-664) antibodyRNF139 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 139 (RNF139) (AA 565-664) antibodyRNF139 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ring Finger Protein 139 (RNF139) (C-Term) antibodyVerified RNF139 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Ring Finger Protein 139 (RNF139) (AA 604-636) antibodyRNF139 适用: 人 WB 宿主: 兔 Polyclonal RB54248 unconjugated
anti-Ring Finger Protein 139 (RNF139) (N-Term) antibodyRNF139 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 664 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RNF139 (Ring Finger Protein 139 (RNF139))
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别名
- RNF139
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背景
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RNF139 is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP. The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.
Alias Symbols: HRCA1, MGC31961, RCA1, TRC8
Protein Interaction Partner: HM13, HLA-C, UBE2G2, AUP1, UBC, INSIG1, HMGCR, INSIG2, TMUB1, ERLIN2, ERLIN1, SCAP, SEC24B, SREBF2, EIF3A, UBE2U, UBE2Z, UBE2H, COPS5, VHL,
Protein Size: 664 -
分子量
- 76 kDa
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基因ID
- 11236
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NCBI登录号
- NM_007218, NP_009149
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UniProt
- Q8WU17
抗原
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