YY1 抗体 (Middle Region)
Quick Overview for YY1 抗体 (Middle Region) (ABIN2774666)
抗原
See all YY1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- KQLAEFARMK PRKIKEDDAP RTIACPHKGC TKMFRDNSAM RKHLHTHGPR
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交叉反应
- 牛, 犬, 小鸡, 人, 小鼠, 大鼠
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预测反应
- Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 92%
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产品特性
- This is a rabbit polyclonal antibody against YY1. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human YY1
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应用备注
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WB Suggested Anti-YY1 Antibody Titration: 0.2-1 µg/mL
Positive Control: Human Thymus.
Optimal working dilutions should be determined experimentally by the investigator. -
说明
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Antigen size: 414 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- YY1 (YY1 Transcription Factor (YY1))
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别名
- YY1
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背景
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YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.
Alias Symbols: DELTA, NF-E1, UCRBP, INO80S, YIN-YANG-1
Protein Interaction Partner: HDAC1, SMURF2, UBC, SHFM1, RNF2, BMI1, SUZ12, RYBP, GABPB1, GABPA, PCGF2, RING1, EP300, LAMC2, SPRY1, SLC39A7, NR1H2, TESK1, RAF1, NFKB1, GRN, CRKL, ARRB1, SP1, WDHD1, ZNF24, NHP2L1, NCL, ZNF830, APP, ZNF638, EED, SMAD3, SMAD2, EZH2, SUMO1, SUMO3, INO80E,
Protein Size: 414 -
分子量
- 45 kDa
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基因ID
- 7528
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NCBI登录号
- NM_003403, NP_003394
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UniProt
- P25490
抗原
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