DMRT1 抗体 (N-Term)
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- 抗原 See all DMRT1 抗体
- DMRT1 (Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))
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抗原表位
- N-Term
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适用
- 人, Cow, 犬, 兔, Pig
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DMRT1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- PNDEAFSKPS TPSEAPHAPG VPPQGRAGGF GKASGALVGA ASGSSAGGSS
- 交叉反应
- 牛, 犬, 人, 猪
- 预测反应
- Cow: 78%, Dog: 85%, Human: 100%, Pig: 78%, Rabbit: 92%
- 产品特性
- This is a rabbit polyclonal antibody against DMRT1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human DMRT1
- Top Product
- Discover our top product DMRT1 Primary Antibody
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- 应用备注
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WB Suggested Anti-DMRT1 Antibody Titration: 0.2-1 µg/mL
Positive Control: Human brain.
Optimal working dilutions should be determined experimentally by the investigator. - 说明
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Antigen size: 373 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- DMRT1 (Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))
- 别名
- DMRT1 (DMRT1 产品)
- 别名
- DMT1 antibody, DMRT1 antibody, zgc:136676 antibody, dmrt1 antibody, dmrt1-alpha antibody, dmt1 antibody, dmrt1-beta antibody, xdmrt1 antibody, doublesex and mab-3 related transcription factor 1 antibody, doublesex and mab-3 related transcription factor 1 L homeolog antibody, doublesex and mab-3 related transcription factor 1 S homeolog antibody, DMRT1 antibody, Dmrt1 antibody, dmrt1 antibody, dmrt1.L antibody, dmrt1.S antibody
- 背景
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The gene encodes the DMRT1 protein is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. This suggested that DMRT1 may be required for testis development.This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DMT1
Protein Interaction Partner: Dlg4, TRIM29,
Protein Size: 373 - 分子量
- 39 kDa
- 基因ID
- 1761
- NCBI登录号
- NM_021951, NP_068770
- UniProt
- Q9Y5R6
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