DMRT1 抗体 (N-Term)
Quick Overview for DMRT1 抗体 (N-Term) (ABIN2774657)
抗原
See all DMRT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- PNDEAFSKPS TPSEAPHAPG VPPQGRAGGF GKASGALVGA ASGSSAGGSS
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交叉反应
- 牛, 犬, 人, 猪
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预测反应
- Cow: 78%, Dog: 85%, Human: 100%, Pig: 78%, Rabbit: 92%
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产品特性
- This is a rabbit polyclonal antibody against DMRT1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human DMRT1
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anti-Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1) (AA 195-363) antibody
DMRT1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1) (AA 1-373) antibodyDMRT1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G11 unconjugated
anti-Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1) (AA 1-373) antibodyDMRT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1) (AA 1-373) antibodyDMRT1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1) (N-Term) antibodyDMRT1 适用: 人, Cow, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1) (AA 134-373) antibodyDMRT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1) antibodyDMRT1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1) (AA 98-128), (N-Term) antibodyDMRT1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB Suggested Anti-DMRT1 Antibody Titration: 0.2-1 µg/mL
Positive Control: Human brain.
Optimal working dilutions should be determined experimentally by the investigator. -
说明
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Antigen size: 373 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DMRT1 (Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))
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别名
- DMRT1
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背景
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The gene encodes the DMRT1 protein is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. This suggested that DMRT1 may be required for testis development.This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DMT1
Protein Interaction Partner: Dlg4, TRIM29,
Protein Size: 373 -
分子量
- 39 kDa
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基因ID
- 1761
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NCBI登录号
- NM_021951, NP_068770
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UniProt
- Q9Y5R6
抗原
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