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CXCL12 抗体 (Middle Region)

This anti-CXCL12 antibody is a 兔 多克隆 antibody detecting CXCL12 in WB. Suitable for 大鼠, 犬, Pig 和 Cow. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2774605
发货至: 中国

Quick Overview for CXCL12 抗体 (Middle Region) (ABIN2774605)

抗原

See all CXCL12 抗体
CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))

适用

  • 74
  • 27
  • 12
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
大鼠, 犬, Pig, Cow

宿主

  • 77
  • 12
  • 10
  • 1
  • 1
  • 1

克隆类型

  • 80
  • 22
多克隆

标记

  • 64
  • 16
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
This CXCL12 antibody is un-conjugated

应用范围

  • 77
  • 49
  • 34
  • 29
  • 22
  • 7
  • 7
  • 6
  • 5
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 12
    • 7
    • 7
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    序列

    VKHLKILNTP NCALQIVARL KNNNRQVCID PKLKWIQEYL EKALNKRFKM

    预测反应

    Cow: 90%, Dog: 100%, Pig: 100%, Rat: 90%

    产品特性

    This is a rabbit polyclonal antibody against CXCL12. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human CXCL12
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 93 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Yin, Seeberger: "Applications of heparin and heparan sulfate microarrays." in: Methods in enzymology, Vol. 478, pp. 197-218, (2010) (PubMed).

  • 抗原

    CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))

    别名

    CXCL12

    背景

    Stromal cell-derived factors 1-alpha and 1-beta are small cytokines that belong to the intercrine family, members of which activate leukocytes and are often induced by proinflammatory stimuli such as lipopolysaccharide, TNF, or IL1. The intercrines are characterized by the presence of 4 conserved cysteines which form 2 disulfide bonds. They can be classified into 2 subfamilies. In the CC subfamily, which includes beta chemokine, the cysteine residues are adjacent to each other. In the CXC subfamily, which includes alpha chemokine, they are separated by an intervening amino acid. The SDF1 proteins belong to the latter group.
    Alias Symbols: IRH, PBSF, SDF1, TLSF, SDF1A, SDF1B, TPAR1, SCYB12
    Protein Interaction Partner: DAZAP2, CXCR4, CXCL12, DPP4, CD4, FN1, ELANE, MMP2, CTSG, VCAN, PF4,
    Protein Size: 93

    分子量

    11 kDa

    基因ID

    6387

    NCBI登录号

    NM_000609, NP_000600

    UniProt

    P48061

    途径

    Regulation of Cell Size, CXCR4-mediated Signaling Events, Negative Regulation of intrinsic apoptotic Signaling
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