CXCL12 抗体 (Middle Region)
Quick Overview for CXCL12 抗体 (Middle Region) (ABIN2774605)
抗原
See all CXCL12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- VKHLKILNTP NCALQIVARL KNNNRQVCID PKLKWIQEYL EKALNKRFKM
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预测反应
- Cow: 90%, Dog: 100%, Pig: 100%, Rat: 90%
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产品特性
- This is a rabbit polyclonal antibody against CXCL12. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CXCL12
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 93 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Applications of heparin and heparan sulfate microarrays." in: Methods in enzymology, Vol. 478, pp. 197-218, (2010) (PubMed).
: "
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Applications of heparin and heparan sulfate microarrays." in: Methods in enzymology, Vol. 478, pp. 197-218, (2010) (PubMed).
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- CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))
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别名
- CXCL12
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背景
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Stromal cell-derived factors 1-alpha and 1-beta are small cytokines that belong to the intercrine family, members of which activate leukocytes and are often induced by proinflammatory stimuli such as lipopolysaccharide, TNF, or IL1. The intercrines are characterized by the presence of 4 conserved cysteines which form 2 disulfide bonds. They can be classified into 2 subfamilies. In the CC subfamily, which includes beta chemokine, the cysteine residues are adjacent to each other. In the CXC subfamily, which includes alpha chemokine, they are separated by an intervening amino acid. The SDF1 proteins belong to the latter group.
Alias Symbols: IRH, PBSF, SDF1, TLSF, SDF1A, SDF1B, TPAR1, SCYB12
Protein Interaction Partner: DAZAP2, CXCR4, CXCL12, DPP4, CD4, FN1, ELANE, MMP2, CTSG, VCAN, PF4,
Protein Size: 93 -
分子量
- 11 kDa
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基因ID
- 6387
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NCBI登录号
- NM_000609, NP_000600
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UniProt
- P48061
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途径
- Regulation of Cell Size, CXCR4-mediated Signaling Events, Negative Regulation of intrinsic apoptotic Signaling
抗原
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