EXOC2 抗体 (N-Term)
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北京 101111
Quick Overview for EXOC2 抗体 (N-Term) (ABIN2774594)
抗原
See all EXOC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- EXOC2 Antibody - N-terminal region
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序列
- MLDLDNDTRP SVLGHLSQTA SLKRGSSFQS GRDDTWRYKT PHRVAFVEKL
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预测反应
- Cow: 85%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against EXOC2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of human EXOC2
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP73061-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- EXOC2 (Exocyst Complex Component 2 (EXOC2))
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别名
- EXOC2
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背景
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Background Information: The protein encoded by this gene is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants.
Gene Name: exocyst complex component 2
Alternative Symbols: SEC5, Sec5p, SEC5L1
Protein Name: exocyst complex component 2
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分子量
- 57kDa
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基因ID
- 55770
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NCBI登录号
- NP_060773
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UniProt
- Q96KP1
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途径
- Peptide Hormone Metabolism, Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis
抗原
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