BDKRB1 抗体 (C-Term)
Quick Overview for BDKRB1 抗体 (C-Term) (ABIN2774418)
抗原
See all BDKRB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- RTREEVSRTR CGGRKDSKTT ALILTLVVAF LVCWAPYHFF AFLEFLFQVQ
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预测反应
- Human: 100%, Mouse: 92%, Pig: 79%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against BDKRB1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human BDKRB1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 353 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- BDKRB1 (Bradykinin Receptor B1 (BDKRB1))
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别名
- BDKRB1
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背景
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Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: B1BKR, B1R, BKB1R, BKR1, BRADYB1
Protein Interaction Partner: GNAQ, MEP1A,
Protein Size: 353 -
分子量
- 40 kDa
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基因ID
- 623
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NCBI登录号
- NM_000710, NP_000701
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UniProt
- P46663
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途径
- ACE Inhibitor Pathway
抗原
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