PDGFA 抗体 (C-Term)
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北京 101111
Quick Overview for PDGFA 抗体 (C-Term) (ABIN2774382)
抗原
See all PDGFA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- PDGFA Antibody - C-terminal region
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序列
- HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTDVR
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预测反应
- Dog: 85%, Guinea Pig: 82%, Human: 100%, Mouse: 85%, Rat: 85%
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产品特性
- This is a rabbit polyclonal antibody against PDGFA. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human PDGFA
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63823-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PDGFA (Platelet Derived Growth Factor A (PDGFA))
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别名
- PDGFA
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背景
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Background Information: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer or as a heterodimer with the platelet-derived growth factor beta polypeptide, where the dimers are connected by disulfide bonds. Studies using knockout mice have shown cellular defects in oligodendrocytes, alveolar smooth muscle cells, and Leydig cells in the testis, knockout mice die either as embryos or shortly after birth. Two splice variants have been identified for this gene.
Gene Name: platelet-derived growth factor alpha polypeptide
Alternative Symbols: PDGF1, PDGF-A
Protein Name: Platelet-derived growth factor subunit A
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分子量
- 21kDa
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基因ID
- 5154
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NCBI登录号
- NP_148983
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UniProt
- P04085
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
抗原
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