FDPS 抗体 (C-Term)
Quick Overview for FDPS 抗体 (C-Term) (ABIN2774296)
抗原
See all FDPS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- VKYKTAFYSF YLPIAAAMYM AGIDGEKEHA NAKKILLEMG EFFQIQDDYL
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预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against FDPS. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 353 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FDPS (Farnesyl Diphosphate Synthase (FDPS))
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别名
- FDPS
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背景
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This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FPPS, FPS
Protein Interaction Partner: UBC, SUMO2, NME1, IDH1, ADSS, NME1-NME2, STAMBP, TALDO1, SORD, PLS3, EGFR, EIF4ENIF1, ATXN1, FGFR1,
Protein Size: 353 -
分子量
- 38 kDa
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基因ID
- 2224
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NCBI登录号
- NM_001135822, NP_001129294
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UniProt
- P14324
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途径
- Regulation of Muscle Cell Differentiation
抗原
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