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DAXX 抗体 (C-Term)

This anti-DAXX antibody is a 兔 多克隆 antibody detecting DAXX in WB. Suitable for 人, 大鼠, 马 和 犬.
产品编号 ABIN2774280
发货至: 中国

Quick Overview for DAXX 抗体 (C-Term) (ABIN2774280)

抗原

See all DAXX 抗体
DAXX (Death-Domain Associated Protein (DAXX))

适用

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人, 大鼠, 马, 犬

宿主

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克隆类型

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多克隆

标记

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This DAXX antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    VSSTSFNGGV SPHNWGDSGP PCKKSRKEKK QTGSGPLGNS YVERQRSVHE

    预测反应

    Dog: 85%, Horse: 92%, Human: 100%, Rat: 86%

    产品特性

    This is a rabbit polyclonal antibody against DAXX. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C-terminal region of Human DAXX
  • 限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeat freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    DAXX (Death-Domain Associated Protein (DAXX))

    别名

    DAXX

    背景

    This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination.
    Protein Interaction Partner: FAM9B, SSX2IP, SUMO1, UBE2I, UBC, GOLGA2, CARD9, PBXIP1, CDCA7L, NECAB2, RASSF1, PML, MDM2, H3F3A, DNMT1, TP53, ATRX, CARM1, PRMT1, WHSC1L1, CUL3, SPOP, HIPK2, PDCD4, DNMT3A, USP7, UBB, RELB, DAXX, CREB1, CBS, ATM, HIST1H4F, HIST1H3C, TRAF3, HIST4H4, BTBD
    Protein Size: 710

    分子量

    78 kDa

    基因ID

    1616

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway
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