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FBXW4 抗体 (N-Term)

FBXW4 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 犬 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2774192
发货至: 中国
  • 抗原 See all FBXW4 抗体
    FBXW4 (F-Box and WD Repeat Domain Containing 4 (FBXW4))
    抗原表位
    • 14
    • 14
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 32
    • 11
    • 9
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 犬
    宿主
    • 34
    • 2
    克隆类型
    • 36
    多克隆
    标记
    • 17
    • 5
    • 4
    • 4
    • 3
    • 3
    This FBXW4 antibody is un-conjugated
    应用范围
    • 29
    • 27
    • 9
    • 4
    • 3
    • 3
    Western Blotting (WB)
    序列
    RQMPWMQLED DSLYISQANF ILAYQFRPDG ASLNRRPLGV FAGHDEDVCH
    预测反应
    Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against FBXW4. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N-terminal region of human FBXW4
    Top Product
    Discover our top product FBXW4 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeat freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    FBXW4 (F-Box and WD Repeat Domain Containing 4 (FBXW4))
    别名
    FBXW4 (FBXW4 产品)
    别名
    dac antibody, hag antibody, hagoromo antibody, wu:fk63g06 antibody, FBXW4 antibody, DAC antibody, FBW4 antibody, FBWD4 antibody, SHFM3 antibody, SHSF3 antibody, Dac antibody, Fbw4 antibody, dactylin antibody, dactylyn antibody, F-box and WD repeat domain containing 4 antibody, F-box and WD-40 domain protein 4 antibody, fbxw4 antibody, FBXW4 antibody, Fbxw4 antibody
    背景
    This gene is a member of the F-box/WD-40 gene family, which recruit specific target proteins through their WD-40 protein-protein binding domains for ubiquitin mediated degradation. In mouse, a highly similar protein is thought to be responsible for maintaining the apical ectodermal ridge of developing limb buds, disruption of the mouse gene results in the absence of central digits, underdeveloped or absent metacarpal/metatarsal bones and syndactyly. This phenotype is remarkably similar to split hand-split foot malformation in humans, a clinically heterogeneous condition with a variety of modes of transmission. An autosomal recessive form has been mapped to the chromosomal region where this gene is located, and complex rearrangements involving duplications of this gene and others have been associated with the condition. A pseudogene of this locus has been mapped to one of the introns of the BCR gene on chromosome 22.
    Alias Symbols: DAC, FBW4, FBWD4, SHFM3, SHSF3
    Protein Size: 325
    分子量
    35 kDa
    基因ID
    6468
    NCBI登录号
    NM_022039, NP_071322
    UniProt
    P57775
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