FBXW4 抗体 (N-Term)
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北京 101111
Quick Overview for FBXW4 抗体 (N-Term) (ABIN2774192)
抗原
See all FBXW4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- RQMPWMQLED DSLYISQANF ILAYQFRPDG ASLNRRPLGV FAGHDEDVCH
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预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against FBXW4. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of human FBXW4
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anti-F-Box and WD Repeat Domain Containing 4 (FBXW4) (AA 143-412) antibody
FBXW4 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 4 (FBXW4) (AA 341-370), (C-Term) antibodyFBXW4 适用: 人 WB 宿主: 兔 Polyclonal RB42400 unconjugated
anti-F-Box and WD Repeat Domain Containing 4 (FBXW4) (AA 41-140) antibodyFBXW4 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 4 (FBXW4) (AA 5-186) antibodyFBXW4 适用: 人, 大鼠 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 4 (FBXW4) (AA 1-412) antibodyFBXW4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 4 (FBXW4) (AA 334-383) antibodyFBXW4 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 犬, 猴, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 4 (FBXW4) (C-Term) antibodyFBXW4 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 犬 WB 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FBXW4 (F-Box and WD Repeat Domain Containing 4 (FBXW4))
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别名
- FBXW4
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背景
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This gene is a member of the F-box/WD-40 gene family, which recruit specific target proteins through their WD-40 protein-protein binding domains for ubiquitin mediated degradation. In mouse, a highly similar protein is thought to be responsible for maintaining the apical ectodermal ridge of developing limb buds, disruption of the mouse gene results in the absence of central digits, underdeveloped or absent metacarpal/metatarsal bones and syndactyly. This phenotype is remarkably similar to split hand-split foot malformation in humans, a clinically heterogeneous condition with a variety of modes of transmission. An autosomal recessive form has been mapped to the chromosomal region where this gene is located, and complex rearrangements involving duplications of this gene and others have been associated with the condition. A pseudogene of this locus has been mapped to one of the introns of the BCR gene on chromosome 22.
Alias Symbols: DAC, FBW4, FBWD4, SHFM3, SHSF3
Protein Size: 325 -
分子量
- 35 kDa
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基因ID
- 6468
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NCBI登录号
- NM_022039, NP_071322
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UniProt
- P57775
抗原
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