Acylglycerol Kinase 抗体 (N-Term)
Quick Overview for Acylglycerol Kinase 抗体 (N-Term) (ABIN2774178)
抗原
See all Acylglycerol Kinase (AGK) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- KKLLELMENT DVIIVAGGDG TLQEVVTGVL RRTDEATFSK IPIGFIPLGE
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预测反应
- Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against AGK. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human AGK
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 422 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Acylglycerol Kinase (AGK)
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别名
- AGK
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背景
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AGK is a lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. AGK does not phosphorylate sphingosine. Overexpression of AGK increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth.
Alias Symbols: FLJ10842, MULK, MTDPS10
Protein Interaction Partner: PCSK9, UBC, RNF2, BMI1, PARK2, FBXO6, UBD, CUL3, AGO4, RYK, ICT1, SNX4, PDLIM1, HCK,
Protein Size: 422 -
分子量
- 47 kDa
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基因ID
- 55750
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NCBI登录号
- NM_018238, NP_060708
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UniProt
- Q53H12
抗原
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