Mre11 抗体 (N-Term)
Quick Overview for Mre11 抗体 (N-Term) (ABIN2774155)
抗原
See all Mre11 (MRE11A) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
序列
- DTFVTLDEIL RLAQENEVDF ILLGGDLFHE NKPSRKTLHT CLELLRKYCM
-
预测反应
- Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 93%
-
产品特性
- This is a rabbit polyclonal antibody against MRE11A. It was validated on Western Blot.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human MRE11A
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 708 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
-
别名
- MRE11A
-
背景
-
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog, this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Alias Symbols: ATLD, HNGS1, MRE11, MRE11B
Protein Interaction Partner: HUWE1, CIAO1, ATRX, BRCA1, RPA3, RPA2, RPA1, EED, ABCF1, C14orf166, RTCB, RPL26L1, NELFB, IGF2BP3, LRRFIP1, MAP7, EIF2B2, EIF2B3, YBX3, RPL27, RFC4, QARS, NMT1, HNRNPM, ILF2, HNRNPU, HNRNPA2B1, FLII, DHX9, DDX1, LMNA, PAN2, UBC, MCM2, GINS1, MDC1, RNF8, C
Protein Size: 708 -
分子量
- 80 kDa
-
基因ID
- 4361
-
NCBI登录号
- NM_005591, NP_005582
-
UniProt
- P49959
-
途径
- DNA Damage Repair
抗原
-