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CHMP2B 抗体 (N-Term)

CHMP2B 适用: 人, 小鼠, 大鼠, Pig, 兔, Cow, 犬, 马, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2774093
发货至: 中国
  • 抗原 See all CHMP2B 抗体
    CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))
    抗原表位
    • 15
    • 14
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    N-Term
    适用
    人, 小鼠, 大鼠, Pig, 兔, Cow, 犬, 马, 豚鼠, 斑马鱼
    宿主
    • 51
    • 3
    • 2
    克隆类型
    • 52
    • 4
    多克隆
    标记
    • 25
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This CHMP2B antibody is un-conjugated
    应用范围
    • 45
    • 21
    • 20
    • 14
    • 13
    • 7
    • 7
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    ASLFKKKTVD DVIKEQNREL RGTQRAIIRD RAALEKQEKQ LELEIKKMAK
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
    产品特性
    This is a rabbit polyclonal antibody against Chmp2b. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N-terminal region of Rat Chmp2b
    Top Product
    Discover our top product CHMP2B Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 213 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))
    别名
    Chmp2b (CHMP2B 产品)
    别名
    ALS17 antibody, CHMP2.5 antibody, DMT1 antibody, VPS2-2 antibody, VPS2B antibody, 1190006E07Rik antibody, RGD1306781 antibody, chmp2b antibody, chmp2bl antibody, zgc:77025 antibody, si:ch211-224m9.5 antibody, CHMP2B antibody, cg4618 antibody, chmp2.5 antibody, dmt1 antibody, vps2-2 antibody, vps2b antibody, CHMP2b-B antibody, chmp2b-a antibody, chmp2b-b antibody, charged multivesicular body protein 2B antibody, charged multivesicular body protein 2Bb antibody, charged multivesicular body protein 2Ba antibody, charged multivesicular body protein 2B pseudogene antibody, charged multivesicular body protein 2B S homeolog antibody, charged multivesicular body protein 2B L homeolog antibody, CHMP2B antibody, Chmp2b antibody, chmp2bb antibody, chmp2ba antibody, LOC747711 antibody, chmp2b.S antibody, chmp2b.L antibody
    背景
    Chmp2b is involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Chmp2b recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Chmp2b redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In conjunction with the ESCRT machinery Chmp2b also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis. Involved in cytokinesis .
    Alias Symbols: RGD1306781
    Protein Size: 213
    分子量
    23 kDa
    基因ID
    363720
    NCBI登录号
    XM_001063932, XP_001063932
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