CHMP2B 抗体 (N-Term)
Quick Overview for CHMP2B 抗体 (N-Term) (ABIN2774093)
抗原
See all CHMP2B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- ASLFKKKTVD DVIKEQNREL RGTQRAIIRD RAALEKQEKQ LELEIKKMAK
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against Chmp2b. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Rat Chmp2b
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anti-Charged Multivesicular Body Protein 2B (CHMP2B) (AA 1-213) antibody
CHMP2B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 2B (CHMP2B) (AA 1-213) antibodyCHMP2B 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 2B (CHMP2B) (AA 1-213) antibodyCHMP2B 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 2B (CHMP2B) antibodyCHMP2B 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 2B (CHMP2B) (AA 31-120) antibodyCHMP2B 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Charged Multivesicular Body Protein 2B (CHMP2B) (AA 1-213) antibodyCHMP2B 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2H6-1E6 unconjugated
anti-Charged Multivesicular Body Protein 2B (CHMP2B) (AA 1-30), (N-Term) antibodyCHMP2B 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33284 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 213 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CHMP2B (Charged Multivesicular Body Protein 2B (CHMP2B))
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别名
- Chmp2b
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背景
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Chmp2b is involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Chmp2b recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Chmp2b redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In conjunction with the ESCRT machinery Chmp2b also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis. Involved in cytokinesis .
Alias Symbols: RGD1306781
Protein Size: 213 -
分子量
- 23 kDa
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基因ID
- 363720
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NCBI登录号
- XM_001063932, XP_001063932
抗原
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