APH1B 抗体 (C-Term)
Quick Overview for APH1B 抗体 (C-Term) (ABIN2774063)
抗原
See all APH1B (Aph1b) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- YYGINLASAF IILVLMGTWA FLAAGGSCRS LKLCLLCQDK NFLLYNQRSR
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预测反应
- Cow: 77%, Dog: 85%, Guinea Pig: 92%, Horse: 77%, Human: 100%, Mouse: 92%, Rabbit: 85%, Rat: 92%
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产品特性
- This is a rabbit polyclonal antibody against APH1B. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 216 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))
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别名
- APH1B
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背景
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This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein.
Alias Symbols: APH-1B, DKFZp564D0372, FLJ33115, PRO1328, PSFL, TAAV688
Protein Interaction Partner: UBC, PSENEN, NCSTN, PSEN2, PSEN1,
Protein Size: 216 -
分子量
- 23 kDa
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基因ID
- 83464
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NCBI登录号
- NM_001145646, NP_001139118
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UniProt
- Q564N3
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途径
- Notch Signaling, Neurotrophin Signaling Pathway
抗原
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