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ACE2 抗体 (Middle Region)

There is 1 publication for this product available. The 兔 多克隆 anti-ACE2 antibody is suitable to detect ACE2 in samples from 人, 小鼠, 大鼠, 豚鼠, Pig, Cow, 犬, 马 和 兔. It has been validated for WB 和 IHC.
产品编号 ABIN2774060
发货至: 中国
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Quick Overview for ACE2 抗体 (Middle Region) (ABIN2774060)

抗原

See all ACE2 抗体
ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

适用

人, 小鼠, 大鼠, 豚鼠, Pig, Cow, 犬, 马, 兔

宿主

  • 173
  • 43
  • 6
  • 1
兔

克隆类型

  • 141
  • 82
多克隆

标记

  • 112
  • 20
  • 14
  • 10
  • 9
  • 7
  • 3
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  • 3
  • 3
  • 3
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  • 1
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This ACE2 antibody is un-conjugated

应用范围

  • 153
  • 78
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  • 63
  • 39
  • 21
  • 20
  • 19
  • 19
  • 17
  • 12
  • 6
  • 3
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  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 16
    • 15
    • 13
    • 12
    • 12
    • 10
    • 9
    • 8
    • 8
    • 8
    • 8
    • 5
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    • 2
    • 1
    • 1
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    Middle Region

    原理

    ACE2 Antibody - middle region

    序列

    FVTAPKNVSD IIPRTEVEKA IRMSRSRIND AFRLNDNSLE FLGIQPTLGP

    预测反应

    Cow: 93%, Dog: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 86%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against ACE2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human ACE2
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53751-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • Mak, Chin, Cunningham, Habib, Torresi, Sharland, Alexander, Angus, Herath: "ACE2 Therapy Using Adeno-associated Viral Vector Inhibits Liver Fibrosis in Mice." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 23, Issue 9, pp. 1434-43, (2015) (PubMed).

  • 抗原

    ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

    别名

    ACE2

    背景

    Background Information: ACE2 belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This protein catalyzes the cleavage of angiotensin I into angiotensin 1-9. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Gene Name: Angiotensin I converting enzyme (peptidyl-dipeptidase A) 2

    Alternative Symbols: ACEH

    Protein Name: Angiotensin-converting enzyme 2

    分子量

    89kDa

    基因ID

    59272

    NCBI登录号

    NP_068576

    UniProt

    Q9BYF1

    途径

    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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