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ACE2 抗体 (Middle Region)

This anti-ACE2 antibody is a 兔 多克隆 antibody detecting ACE2 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, Pig, 犬, 兔, Cow, 豚鼠 和 马. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN2774060
发货至: 中国

Quick Overview for ACE2 抗体 (Middle Region) (ABIN2774060)

抗原

See all ACE2 抗体
ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

适用

人, 小鼠, 大鼠, Pig, 犬, 兔, Cow, 豚鼠, 马

宿主

  • 147
  • 45
  • 6
  • 1

克隆类型

  • 126
  • 73
多克隆

标记

  • 121
  • 17
  • 12
  • 8
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ACE2 antibody is un-conjugated

应用范围

  • 157
  • 86
  • 78
  • 50
  • 41
  • 36
  • 30
  • 18
  • 17
  • 14
  • 10
  • 6
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 19
    • 16
    • 12
    • 8
    • 8
    • 8
    • 8
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    序列

    FVTAPKNVSD IIPRTEVEKA IRMSRSRIND AFRLNDNSLE FLGIQPTLGP

    预测反应

    Cow: 93%, Dog: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 86%, Rat: 93%

    产品特性

    This is a rabbit polyclonal antibody against ACE2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human ACE2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 805 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Mak, Chin, Cunningham, Habib, Torresi, Sharland, Alexander, Angus, Herath: "ACE2 Therapy Using Adeno-associated Viral Vector Inhibits Liver Fibrosis in Mice." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 23, Issue 9, pp. 1434-43, (2015) (PubMed).

  • 抗原

    ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

    别名

    ACE2

    背景

    ACE2 belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This protein catalyzes the cleavage of angiotensin I into angiotensin 1-9. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: ACEH, DKFZP434A014
    Protein Interaction Partner: ACE2, AGT, CALM1, NTS, GHRL,
    Protein Size: 805

    分子量

    89 kDa

    基因ID

    59272

    NCBI登录号

    NM_021804, NP_068576

    UniProt

    Q9BYF1

    途径

    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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