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PNKP 抗体 (N-Term)

This anti-PNKP antibody is a 兔 多克隆 antibody detecting PNKP in WB. Suitable for 人, 小鼠, 大鼠, 犬, Cow, 豚鼠 和 马.
产品编号 ABIN2774011
发货至: 中国

Quick Overview for PNKP 抗体 (N-Term) (ABIN2774011)

抗原

See all PNKP 抗体
PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

适用

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人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马

宿主

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克隆类型

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多克隆

标记

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This PNKP antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    MGEVEAPGRL WLESPPGGAP PIFLPSDGQA LVLGRGPLTQ VTDRKCSRTQ

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against PNKP. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human PNKP
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 521 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

    别名

    PNKP

    背景

    This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.
    Alias Symbols: PNK, MCSZ, EIEE10
    Protein Interaction Partner: ZNF639, IKZF1, TNIP1, ZBTB14, RPA3, RPA2, RPA1, EED, rev, KDM1A, SUV39H1, HNRNPU, GZMK, XRCC6, CDK11B, PARP1, MCM3, SMAD5, LIG4, XRCC1, TCOF1, SSRP1, PRKDC, NRD1, NASP, MCM5, C18orf25, UBE2O, GEMIN4, AGTPBP1, PNKP, SUPT16H, VPRBP, NOLC1, TRIM26, XRCC5, XR
    Protein Size: 521

    分子量

    57 kDa

    基因ID

    11284

    NCBI登录号

    NM_007254, NP_009185

    UniProt

    Q96T60

    途径

    DNA Damage Repair, Nucleotide Phosphorylation
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