CSK 抗体 (Middle Region)
Quick Overview for CSK 抗体 (Middle Region) (ABIN2774001)
抗原
See all CSK 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
序列
- SEDNVAKVSD FGLTKEASST QDTGKLPVKW TAPEALREKK FSTKSDVWSF
-
预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%
-
产品特性
- This is a rabbit polyclonal antibody against CSK. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human CSK
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 450 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- CSK (C-Src tyrosine Kinase (CSK))
-
别名
- CSK
-
背景
-
CSK specifically phosphorylates 'Tyr-504' on LCK, which acts as a negative regulatory site.CSK can also act on the LYN and FYN kinases.
Alias Symbols: MGC117393
Protein Interaction Partner: UBC, EGFR, TNRC6B, PAG1, RGS16, ZAP70, CD247, CD3E, KHDRBS1, TENC1, FRK, ARRB2, ARRB1, AKT1, GRB2, VCP, ID3, FHL2, SRCIN1, ZNF212, G3BP1, UBASH3B, SHC1, CBL, JUN, ELAVL1, Csk, MAPK15, DOK3, PTPN22, PTPN18, SIT1, TLR3, LAIR1, DOK1, PXN, PLD2, PRKACA, DAB2,
Protein Size: 450 -
分子量
- 51 kDa
-
基因ID
- 1445
-
NCBI登录号
- NM_004383, NP_004374
-
UniProt
- P41240
-
途径
- TCR Signaling, EGFR Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events
抗原
-