HLA-F 抗体 (N-Term)
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Quick Overview for HLA-F 抗体 (N-Term) (ABIN2773941)
抗原
See all HLA-F (HLAF) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- EAGSHTLQGM NGCDMGPDGR LLRGYHQHAY DGKDYISLNE DLRSWTAADT
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预测反应
- Cow: 93%, Human: 100%, Pig: 100%
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产品特性
- This is a rabbit polyclonal antibody against HLA-F. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human HLA-F
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anti-HLA Class I alpha F (HLAF) antibody (PE)
HLAF 适用: 人 FACS 宿主: 小鼠 Monoclonal 3D11 PE
anti-HLA Class I alpha F (HLAF) antibodyHLAF 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 3D11 unconjugated
anti-HLA Class I alpha F (HLAF) (AA 194-303) antibodyHLAF 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-HLA Class I alpha F (HLAF) antibodyHLAF 适用: 人 WB 宿主: 小鼠 Monoclonal 25GB7425 unconjugated
anti-HLA Class I alpha F (HLAF) (AA 71-120) antibodyHLAF 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-HLA Class I alpha F (HLAF) (AA 110-159) antibodyHLAF 适用: 人, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-HLA Class I alpha F (HLAF) (N-Term) antibodyHLAF 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-HLA Class I alpha F (HLAF) antibodyHLAF 适用: 人 WB, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 442 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- HLA-F (HLAF) (HLA Class I alpha F (HLAF))
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别名
- HLA-F
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背景
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HLA-F belongs to the HLA class I heavy chain paralogues. It is a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene belongs to the HLA class I heavy chain paralogues. It encodes a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene exhibits few polymorphisms. Multiple transcript variants encoding different isoforms have been found for this gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site, resulting in a shorter cytoplasmic domain.
Alias Symbols: CDA12, HLA-5.4, HLA-CDA12, HLAF
Protein Interaction Partner: UBC, LILRB2, LILRB1, TAP1, HLA-F, B2M,
Protein Size: 442 -
分子量
- 48 kDa
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基因ID
- 3134
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NCBI登录号
- NM_001098479, NP_001091949
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UniProt
- P30511
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
抗原
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