PRP19 抗体 (Middle Region)
(1 reference)Quick Overview for PRP19 抗体 (Middle Region) (ABIN2773819)
抗原
See all PRP19 (PRPF19) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- PSVVGAGEPM DLGELVGMTP EIIQKLQDKA TVLTTERKKR GKTVPEELVK
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against PRPF19. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PRPF19
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anti-Pre-mRNA Processing Factor 19 (PRPF19) (AA 1-90) antibody
PRPF19 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E5 unconjugated
anti-Pre-mRNA Processing Factor 19 (PRPF19) (AA 127-416) antibodyPRPF19 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Pre-mRNA Processing Factor 19 (PRPF19) (AA 1-90) antibodyPRPF19 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Pre-mRNA Processing Factor 19 (PRPF19) antibodyPRPF19 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pre-mRNA Processing Factor 19 (PRPF19) (AA 4-33), (N-Term) antibodyPRPF19 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20845 unconjugated
anti-Pre-mRNA Processing Factor 19 (PRPF19) (N-Term) antibodyPRPF19 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pre-mRNA Processing Factor 19 (PRPF19) (AA 151-200) antibodyPRPF19 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 斑马鱼, 豚鼠, Pig, Bat, 猴, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Pre-mRNA Processing Factor 19 (PRPF19) antibodyPRPF19 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pre-mRNA Processing Factor 19 (PRPF19) (Internal Region) antibodyPRPF19 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Pre-mRNA Processing Factor 19 (PRPF19) antibodyPRPF19 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 504 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Proteomic characterisation of pancreatic islet beta-cells stimulated with pancreatic carcinoma cell conditioned medium." in: Journal of clinical pathology, Vol. 62, Issue 9, pp. 802-7, (2009) (PubMed).
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: "Proteomic characterisation of pancreatic islet beta-cells stimulated with pancreatic carcinoma cell conditioned medium." in: Journal of clinical pathology, Vol. 62, Issue 9, pp. 802-7, (2009) (PubMed).
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- PRP19 (PRPF19) (Pre-mRNA Processing Factor 19 (PRPF19))
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别名
- PRPF19
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背景
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PRPF19 plays a role in DNA double-strand break (DSB) repair and pre-mRNA splicing reaction. It binds double-stranded DNA in a sequence-nonspecific manner. PRPF19 acts as a structural component of the nuclear framework. It may also serve as a support for spliceosome binding and activity. It is essential for spliceosome assembly in a oligomerization-dependent manner and might also be important for spliceosome stability. It also may have E3 ubiquitin ligase activity. The PSO4 complex is required in the DNA interstrand cross-links (ICLs) repair process. Overexpression of PRPF19 might extend the cellular life span by increasing the resistance to stress or by improving the DNA repair capacity of the cells.In S. cerevisiae, Pso4 has pleiotropic functions in DNA recombination and in error-prone nonhomologous end-joining DNA repair.[supplied by OMIM].
Alias Symbols: NMP200, PRP19, PSO4, UBOX4, hPSO4, SNEV
Protein Interaction Partner: HUWE1, USP4, UBE2D3, SUMO2, CEP76, CEP250, TUBGCP3, CEP57, VCP, UBC, SUMO1, NEDD8, LIN28A, EXOC7, EXOC3, RPA3, RPA2, RPA1, RNF2, SUZ12, EED, rev, MEPCE, SEC13, PARK2, TARDBP, UBD, CSNK2A2, UCHL5, WHSC1, U2AF1, PRCC, HSP90AA1, HSPB1, FN1, RBM10, vif, CDC40
Protein Size: 504 -
分子量
- 55 kDa
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基因ID
- 27339
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NCBI登录号
- NM_014502, NP_055317
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UniProt
- Q9UMS4
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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