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BHMT 抗体 (N-Term)

BHMT 适用: 人, 小鼠, 大鼠, 犬, 马, 豚鼠, 兔, Cow, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2773785
发货至: 中国
  • 抗原 See all BHMT 抗体
    BHMT (Betaine--Homocysteine S-Methyltransferase (BHMT))
    抗原表位
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 25
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, 马, 豚鼠, 兔, Cow, 斑马鱼
    宿主
    • 17
    • 7
    • 1
    克隆类型
    • 19
    • 6
    多克隆
    标记
    • 25
    This BHMT antibody is un-conjugated
    应用范围
    • 25
    • 14
    • 9
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    AVEHPEAVRQ LHREFLRAGS NVMQTFTFYA SEDKLENRGN YVLEKISGQE
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    产品特性
    This is a rabbit polyclonal antibody against BHMT. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human BHMT
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 406 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Jiang, Hurt, Breen, Stabler, Allen, Orlicky, Maclean: "Sex-specific dysregulation of cysteine oxidation and the methionine and folate cycles in female cystathionine gamma-lyase null mice: a serendipitous model of the methylfolate trap." in: Biology open, Vol. 4, Issue 9, pp. 1154-62, (2015) (PubMed).

    Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

    Maclean, Jiang, Greiner, Allen, Stabler et al.: "Long-term betaine therapy in a murine model of cystathionine beta-synthase deficient homocystinuria: decreased efficacy over time reveals a significant threshold effect between elevated homocysteine ..." in: Molecular genetics and metabolism, Vol. 105, Issue 3, pp. 395-403, (2012) (PubMed).

  • 抗原
    BHMT (Betaine--Homocysteine S-Methyltransferase (BHMT))
    别名
    BHMT (BHMT 产品)
    别名
    BHMT1 antibody, hm:zehn2153 antibody, wu:fb53h01 antibody, wu:fb63c08 antibody, wu:fj64d01 antibody, zgc:123027 antibody, betaine--homocysteine S-methyltransferase antibody, betaine--homocysteine S-methyltransferase L homeolog antibody, betaine-homocysteine methyltransferase antibody, betaine-homocysteine S-methyltransferase antibody, BHMT antibody, bhmt.L antibody, Bhmt antibody, bhmt antibody
    背景
    BHMT is a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in its gene could lead to hyperhomocyst(e)inemia, but such a defect has not yet been observed.Betaine-homocysteine methyltransferase is a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in BHMT could lead to hyperhomocyst(e)inemia,but such a defect has not yet been observed.
    Alias Symbols: BHMT1
    Protein Interaction Partner: BHMT, BBS4, BBS2, BBS1, ALG9, LAMTOR3,
    Protein Size: 406
    分子量
    45 kDa
    基因ID
    635
    NCBI登录号
    NM_001713, NP_001704
    UniProt
    Q93088
    途径
    Methionine Biosynthetic Process
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