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BHMT 抗体 (N-Term)

Name: BHMT 抗体 (N-Term)
SKU: ABIN2773785
Availability: OutOfStock

This anti-BHMT antibody is a 兔多克隆 antibody detecting BHMT in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Cow, 兔和斑马鱼. This Primary Antibody has been cited in 3+ publications.

Host: Rabbit Target Name: BHMT Sample Type: 293T Antibody Dilution: 1. (BHMT 抗体 (N-Term))

Immunohistochemistry (IHC) image for anti-Betaine--Homocysteine S-Methyltransferase (BHMT) (N-Term) antibody (ABIN2773785) (BHMT 抗体 (N-Term))

IHC

WB Suggested Anti-BHMT Antibody Titration: 2. (BHMT 抗体 (N-Term))

Lanes: Lane1: 20 ug rat liver lysate Primary Antibody Dilution: 1:1000 Secondary Antibody: Anti-rabbit HRP Secondary Antibody Dilution: 1:15000 Gene Name: BHMT Submitted by: Anonymous (BHMT 抗体 (N-Term))

Lanes: Lane1: 20 ug rat liver lysate Primary Antibody Dilution: 1:2000 Secondary Antibody: Anti-rabbit HRP Secondary Antibody Dilution: 1:15000 Gene Name: BHMT Submitted by: Anonymous (BHMT 抗体 (N-Term))

Rabbit Anti-BHMT Antibody Paraffin Embedded Tissue: Human Kidney Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4. (BHMT 抗体 (N-Term))

IHC

6 images

(3 references)

产品编号 ABIN2773785

发货至: 中国

Quick Overview for BHMT 抗体 (N-Term) (ABIN2773785)

抗原

See all BHMT 抗体

BHMT (Betaine--Homocysteine S-Methyltransferase (BHMT))

适用

人, 小鼠, 大鼠, 犬, 豚鼠, 马, Cow, 兔, 斑马鱼

宿主

兔

克隆类型

多克隆

标记

This BHMT antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC)

抗原表位
5

4

3

2

1

1

1

1

1

1

1

1

1
N-Term

序列

AVEHPEAVRQ LHREFLRAGS NVMQTFTFYA SEDKLENRGN YVLEKISGQE

预测反应

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

产品特性

This is a rabbit polyclonal antibody against BHMT. It was validated on Western Blot and immunohistochemistry.

纯化方法

Protein A purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human BHMT
anti-Betaine--Homocysteine S-Methyltransferase (BHMT) (C-Term) antibody
Verified BHMT 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Betaine--Homocysteine S-Methyltransferase (BHMT) antibody
BHMT 适用: 人 WB, IF, FACS 宿主: 小鼠 Monoclonal 10B3 unconjugated

anti-Betaine--Homocysteine S-Methyltransferase (BHMT) (AA 177-406) antibody
BHMT 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Betaine--Homocysteine S-Methyltransferase (BHMT) (C-Term) antibody
BHMT 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Cow, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Betaine--Homocysteine S-Methyltransferase (BHMT) (C-Term) antibody
BHMT 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Betaine--Homocysteine S-Methyltransferase (BHMT) antibody
BHMT 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 8C11H5 unconjugated

anti-Betaine--Homocysteine S-Methyltransferase (BHMT) antibody
BHMT 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Betaine--Homocysteine S-Methyltransferase (BHMT) (C-Term) antibody
BHMT 适用: 人, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Betaine--Homocysteine S-Methyltransferase (BHMT) (N-Term) antibody
BHMT 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Betaine--Homocysteine S-Methyltransferase (BHMT) (AA 1-406) antibody
BHMT 适用: 人 WB, ELISA, IF, FACS, ICC 宿主: 小鼠 Monoclonal 3D6 unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 406 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Jiang, Hurt, Breen, Stabler, Allen, Orlicky, Maclean: "Sex-specific dysregulation of cysteine oxidation and the methionine and folate cycles in female cystathionine gamma-lyase null mice: a serendipitous model of the methylfolate trap." in: Biology open, Vol. 4, Issue 9, pp. 1154-62, (2015) (PubMed).

Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

Maclean, Jiang, Greiner, Allen, Stabler et al.: "Long-term betaine therapy in a murine model of cystathionine beta-synthase deficient homocystinuria: decreased efficacy over time reveals a significant threshold effect between elevated homocysteine ..." in: Molecular genetics and metabolism, Vol. 105, Issue 3, pp. 395-403, (2012) (PubMed).
抗原

BHMT (Betaine--Homocysteine S-Methyltransferase (BHMT))

别名

BHMT

背景

BHMT is a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in its gene could lead to hyperhomocyst(e)inemia, but such a defect has not yet been observed.Betaine-homocysteine methyltransferase is a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in BHMT could lead to hyperhomocyst(e)inemia,but such a defect has not yet been observed.
Alias Symbols: BHMT1
Protein Interaction Partner: BHMT, BBS4, BBS2, BBS1, ALG9, LAMTOR3,
Protein Size: 406

分子量

45 kDa

基因ID

635

NCBI登录号

NM_001713, NP_001704

UniProt

Q93088

途径

Methionine Biosynthetic Process