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HCRTR1 抗体 (N-Term)

This anti-HCRTR1 antibody is a 兔 多克隆 antibody detecting HCRTR1 in ELISA. Suitable for 人.
产品编号 ABIN2764055
发货至: 中国

Quick Overview for HCRTR1 抗体 (N-Term) (ABIN2764055)

抗原

See all HCRTR1 抗体
HCRTR1 (Hypocretin (Orexin) Receptor 1 (HCRTR1))

适用

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宿主

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克隆类型

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多克隆

标记

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This HCRTR1 antibody is un-conjugated

应用范围

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ELISA
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    N-Term

    交叉反应

    产品特性

    Ox1r, Hypocretin receptor type 1,As first published in 1998 by Sakurai et al, the initial neuropeptides Orexin A and Orexin B were shown to be important in the regulation of appetite. Continued research now suggests that these peptides also influence a wide range of physiological and behavioral processes such as increased EFG arousal and wakefulness and locomotor activity. In addition to the orexins , two G-protein coupled receptors, designated orexin receptor-1 and orexin receptor-2, have been identified which presumably mediate the signaling events from these neuropeptides1. Recently Orexin Receptors have been found to activate extracellular signal-regulated kinases in CHO cells, namely ERK phosporylation, through Ca2+ influx..2. Further studies seem to indicate a mechanism for orexin receptor mediated cell death and suggest a pathway from GPCRs to apoptosis throughthe MAPK pathways.3

    纯化方法

    Antigen Immunoaffiinity Purification

    免疫原

    Synthetic peptide made to the N terminal of human Orexin Receptor 1

    亚型

    IgG
  • 应用备注

    Antibody can be used for Western blotting at Optimal concentration should be evaluated by serial dilutions.

    限制

    仅限研究用
  • 缓冲液

    Immunoaffinity antibody povided as solution in phosphate buffered saline with 0.08 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
  • 抗原

    HCRTR1 (Hypocretin (Orexin) Receptor 1 (HCRTR1))

    别名

    Orexin Receptor-1

    UniProt

    O43613

    途径

    Feeding Behaviour
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